Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis

The Wnt signaling pathway controls multiple events during embryonic development of multicellular animals and is carcinogenic when aberrantly activated in adults. Breast cancers are dependent on Wnt pathway overactivation mostly through dysregulation of pathway component protein expression, which nec...

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Detalles Bibliográficos
Autores principales: Pellissier, Léonie, Koval, Alexey, Marcourt, Laurence, Ferreira Queiroz, Emerson, Lecoultre, Nicole, Leoni, Sara, Quiros-Guerrero, Luis-Manuel, Barthélémy, Morgane, Duivelshof, Bastiaan L., Guillarme, Davy, Tardy, Sébastien, Eparvier, Véronique, Perron, Karl, Chave, Jérôme, Stien, Didier, Gindro, Katia, Katanaev, Vladimir, Wolfender, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397479/
https://www.ncbi.nlm.nih.gov/pubmed/34458231
http://dx.doi.org/10.3389/fchem.2021.664489

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