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Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?

PURPOSE: The treatment of people with severe obesity and BMI > 50 kg/m(2) is challenging. The present study aims to evaluate the short and mid-term outcomes of one anastomosis gastric bypass (OAGB) with a biliopancreatic limb of 150 cm as a primary bariatric procedure to treat those people in a r...

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Autores principales: Liagre, Arnaud, Martini, Francesco, Kassir, Radwan, Juglard, Gildas, Hamid, Celine, Boudrie, Hubert, Van Haverbeke, Olivier, Antolino, Laura, Debs, Tarek, Petrucciani, Niccolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397657/
https://www.ncbi.nlm.nih.gov/pubmed/34176036
http://dx.doi.org/10.1007/s11695-021-05499-3
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author Liagre, Arnaud
Martini, Francesco
Kassir, Radwan
Juglard, Gildas
Hamid, Celine
Boudrie, Hubert
Van Haverbeke, Olivier
Antolino, Laura
Debs, Tarek
Petrucciani, Niccolo
author_facet Liagre, Arnaud
Martini, Francesco
Kassir, Radwan
Juglard, Gildas
Hamid, Celine
Boudrie, Hubert
Van Haverbeke, Olivier
Antolino, Laura
Debs, Tarek
Petrucciani, Niccolo
author_sort Liagre, Arnaud
collection PubMed
description PURPOSE: The treatment of people with severe obesity and BMI > 50 kg/m(2) is challenging. The present study aims to evaluate the short and mid-term outcomes of one anastomosis gastric bypass (OAGB) with a biliopancreatic limb of 150 cm as a primary bariatric procedure to treat those people in a referral center for bariatric surgery. MATERIAL AND METHODS: Data of patients who underwent OAGB for severe obesity with BMI > 50 kg/m(2) between 2010 and 2017 were collected prospectively and analyzed retrospectively. Follow-up comprised clinical and biochemical assessment at 1, 3, 6, 12, 18, and 24 months postoperatively, and once a year thereafter. RESULTS: Overall, 245 patients underwent OAGB. Postoperative mortality was null, and early morbidity was observed in 14 (5.7%) patients. At 24 months, the percentage total weight loss (%TWL) was 43.2 ± 9, and percentage excess weight loss (%EWL) was 80 ± 15.7 (184 patients). At 60 months, %TWL was 41.9 ± 10.2, and %EWL was 78.1 ± 18.3 (79 patients). Conversion to Roux-en-Y gastric bypass was needed in three (1.2%) patients for reflux resistant to medical treatment. Six patients (2.4%) had reoperation for an internal hernia during follow-up. Anastomotic ulcers occurred in three (1.2%) patients. Only two patients (0.8%) underwent a second bariatric surgery for insufficient weight loss. CONCLUSION: OAGB with a biliopancreatic limb of 150 cm is feasible and associated with sustained weight loss in the treatment of severe obesity with BMI > 50 kg/m(2). Further randomized studies are needed to compare OAGB with other bariatric procedures in this setting. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-83976572021-09-15 Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50? Liagre, Arnaud Martini, Francesco Kassir, Radwan Juglard, Gildas Hamid, Celine Boudrie, Hubert Van Haverbeke, Olivier Antolino, Laura Debs, Tarek Petrucciani, Niccolo Obes Surg Original Contributions PURPOSE: The treatment of people with severe obesity and BMI > 50 kg/m(2) is challenging. The present study aims to evaluate the short and mid-term outcomes of one anastomosis gastric bypass (OAGB) with a biliopancreatic limb of 150 cm as a primary bariatric procedure to treat those people in a referral center for bariatric surgery. MATERIAL AND METHODS: Data of patients who underwent OAGB for severe obesity with BMI > 50 kg/m(2) between 2010 and 2017 were collected prospectively and analyzed retrospectively. Follow-up comprised clinical and biochemical assessment at 1, 3, 6, 12, 18, and 24 months postoperatively, and once a year thereafter. RESULTS: Overall, 245 patients underwent OAGB. Postoperative mortality was null, and early morbidity was observed in 14 (5.7%) patients. At 24 months, the percentage total weight loss (%TWL) was 43.2 ± 9, and percentage excess weight loss (%EWL) was 80 ± 15.7 (184 patients). At 60 months, %TWL was 41.9 ± 10.2, and %EWL was 78.1 ± 18.3 (79 patients). Conversion to Roux-en-Y gastric bypass was needed in three (1.2%) patients for reflux resistant to medical treatment. Six patients (2.4%) had reoperation for an internal hernia during follow-up. Anastomotic ulcers occurred in three (1.2%) patients. Only two patients (0.8%) underwent a second bariatric surgery for insufficient weight loss. CONCLUSION: OAGB with a biliopancreatic limb of 150 cm is feasible and associated with sustained weight loss in the treatment of severe obesity with BMI > 50 kg/m(2). Further randomized studies are needed to compare OAGB with other bariatric procedures in this setting. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2021-06-26 2021 /pmc/articles/PMC8397657/ /pubmed/34176036 http://dx.doi.org/10.1007/s11695-021-05499-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Contributions
Liagre, Arnaud
Martini, Francesco
Kassir, Radwan
Juglard, Gildas
Hamid, Celine
Boudrie, Hubert
Van Haverbeke, Olivier
Antolino, Laura
Debs, Tarek
Petrucciani, Niccolo
Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title_full Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title_fullStr Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title_full_unstemmed Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title_short Is One Anastomosis Gastric Bypass with a Biliopancreatic Limb of 150 cm Effective in the Treatment of People with Severe Obesity with BMI > 50?
title_sort is one anastomosis gastric bypass with a biliopancreatic limb of 150 cm effective in the treatment of people with severe obesity with bmi > 50?
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397657/
https://www.ncbi.nlm.nih.gov/pubmed/34176036
http://dx.doi.org/10.1007/s11695-021-05499-3
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