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Deficient Chaperone-Mediated Autophagy Promotes Lipid Accumulation in Macrophage

Chaperone-mediated autophagy (CMA) serves as a critical upstream regulator of lipophagy and lipid metabolism in hepatocyte. However, the role of CMA in lipid metabolism of macrophage, the typical component of atherosclerotic plaque, remains unclear. In our study, LAMP-2A (L2A, a CMA marker) was redu...

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Detalles Bibliográficos
Autores principales:	Qiao, Lei, Wang, He-feng, Xiang, Lei, Ma, Jing, Zhu, Qiang, Xu, Dan, Zheng, Hui, Peng, Jie-qiong, Zhang, Sen, Lu, Hui-xia, Chen, Wen-qiang, Zhang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397667/ https://www.ncbi.nlm.nih.gov/pubmed/32285315 http://dx.doi.org/10.1007/s12265-020-09986-3

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