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Integrin-Linked Kinase Activation Prevents Ventricular Arrhythmias Induced by Ischemia/Reperfusion Via Inhibition of Connexin 43 Remodeling

Ischemia reperfusion (I/R)-induced arrhythmia is a serious complication in patients with cardiac infarction. Remodeling of connexin (Cx) 43, manifested as phosphorylation, contributes significantly to arrhythmogenesis. Integrin-linked kinase (ILK) attenuated ventricular remodeling and improved cardi...

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Detalles Bibliográficos
Autores principales: Zhou, Ping, Yang, Xiaoli, Yang, Dezhong, Jiang, Xin, Wang, Wei Eric, Yue, Rongchuan, Fang, Yuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397684/
https://www.ncbi.nlm.nih.gov/pubmed/32144627
http://dx.doi.org/10.1007/s12265-020-09979-2