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Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery

This study aimed to investigate the incidence of and risk factors for postoperative new-onset deep venous thrombosis (PNO-DVT) following intertrochanteric fracture surgery. Information on 1672 patients who underwent intertrochanteric fracture surgery at our hospital between January 2016 and December...

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Autores principales: Zhao, Kuo, Zhang, Junzhe, Li, Junyong, Meng, Hongyu, Hou, Zhiyong, Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397722/
https://www.ncbi.nlm.nih.gov/pubmed/34453081
http://dx.doi.org/10.1038/s41598-021-96937-w
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author Zhao, Kuo
Zhang, Junzhe
Li, Junyong
Meng, Hongyu
Hou, Zhiyong
Zhang, Yingze
author_facet Zhao, Kuo
Zhang, Junzhe
Li, Junyong
Meng, Hongyu
Hou, Zhiyong
Zhang, Yingze
author_sort Zhao, Kuo
collection PubMed
description This study aimed to investigate the incidence of and risk factors for postoperative new-onset deep venous thrombosis (PNO-DVT) following intertrochanteric fracture surgery. Information on 1672 patients who underwent intertrochanteric fracture surgery at our hospital between January 2016 and December 2019 was extracted from a prospective hip fracture database. Demographic information, surgical data, and preoperative laboratory indices were analysed. Receiver operating characteristic curve analysis, univariate analyses and binary logistic regression analyses were performed. The incidences of postoperative deep venous thrombosis (DVT) and PNO-DVT in inpatients after intertrochanteric fracture surgery were 11.5% (202 of 1751 patients) and 7.4% (123 of 1672 patients), respectively. PNO-DVT accounted for 60.9% of postoperative DVT. Additionally, there were 20 cases of central thrombosis (16.3%), 82 cases of peripheral thrombosis (66.7%), and 21 cases of mixed thrombosis (17.1%). In addition, 82.1% of PNO-DVTs were diagnosed within 8 days after surgery. The multivariate analysis revealed that age > 70 years, duration of surgery (> 197 min), type of anaesthesia (general), and comorbidities (≥ 3) were independent risk factors for the development of PNO-DVT after intertrochanteric fracture surgery. This study demonstrated a high incidence of PNO-DVT in inpatients after intertrochanteric fracture surgery. Therefore, postoperative examination for DVT should be routinely conducted for patients.
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spelling pubmed-83977222021-09-01 Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery Zhao, Kuo Zhang, Junzhe Li, Junyong Meng, Hongyu Hou, Zhiyong Zhang, Yingze Sci Rep Article This study aimed to investigate the incidence of and risk factors for postoperative new-onset deep venous thrombosis (PNO-DVT) following intertrochanteric fracture surgery. Information on 1672 patients who underwent intertrochanteric fracture surgery at our hospital between January 2016 and December 2019 was extracted from a prospective hip fracture database. Demographic information, surgical data, and preoperative laboratory indices were analysed. Receiver operating characteristic curve analysis, univariate analyses and binary logistic regression analyses were performed. The incidences of postoperative deep venous thrombosis (DVT) and PNO-DVT in inpatients after intertrochanteric fracture surgery were 11.5% (202 of 1751 patients) and 7.4% (123 of 1672 patients), respectively. PNO-DVT accounted for 60.9% of postoperative DVT. Additionally, there were 20 cases of central thrombosis (16.3%), 82 cases of peripheral thrombosis (66.7%), and 21 cases of mixed thrombosis (17.1%). In addition, 82.1% of PNO-DVTs were diagnosed within 8 days after surgery. The multivariate analysis revealed that age > 70 years, duration of surgery (> 197 min), type of anaesthesia (general), and comorbidities (≥ 3) were independent risk factors for the development of PNO-DVT after intertrochanteric fracture surgery. This study demonstrated a high incidence of PNO-DVT in inpatients after intertrochanteric fracture surgery. Therefore, postoperative examination for DVT should be routinely conducted for patients. Nature Publishing Group UK 2021-08-27 /pmc/articles/PMC8397722/ /pubmed/34453081 http://dx.doi.org/10.1038/s41598-021-96937-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhao, Kuo
Zhang, Junzhe
Li, Junyong
Meng, Hongyu
Hou, Zhiyong
Zhang, Yingze
Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title_full Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title_fullStr Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title_full_unstemmed Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title_short Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
title_sort incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397722/
https://www.ncbi.nlm.nih.gov/pubmed/34453081
http://dx.doi.org/10.1038/s41598-021-96937-w
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