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Imaging carbonic anhydrase IX as a method for monitoring hypoxia-related radioresistance in preclinical head and neck cancer models

BACKGROUND AND PURPOSE: Tumor hypoxia is an important cause of radioresistance and is associated with poor outcome. SPECT (Single-photon emission computed tomography) imaging enables visualizing tumor characteristics. We investigated the SPECT-radiotracer [(111)In]-girentuximab-F(ab’)(2) to image Ca...

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Detalles Bibliográficos
Autores principales: Huizing, Fokko J., Hoeben, Bianca A.W., Lok, Jasper, Boerman, Otto C., Heskamp, Sandra, Bussink, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397885/
https://www.ncbi.nlm.nih.gov/pubmed/34485720
http://dx.doi.org/10.1016/j.phro.2021.08.004

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