Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats

We found that curcumin, a p300 histone acetyltransferase (HAT) inhibitor, prevents cardiac hypertrophy and systolic dysfunction at the stage of chronic heart failure in Dahl salt-sensitive rats (DS). It is unclear whether curcumin suppresses the development of hypertension-induced left ventricular h...

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Detalles Bibliográficos
Autores principales: Sunagawa, Yoichi, Funamoto, Masafumi, Shimizu, Kana, Shimizu, Satoshi, Sari, Nurmila, Katanasaka, Yasufumi, Miyazaki, Yusuke, Kakeya, Hideaki, Hasegawa, Koji, Morimoto, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397934/
https://www.ncbi.nlm.nih.gov/pubmed/34444769
http://dx.doi.org/10.3390/nu13082608

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