Synthesis of Novel Biologically Active Proflavine Ureas Designed on the Basis of Predicted Entropy Changes

A novel series of proflavine ureas, derivatives 11a–11i, were synthesized on the basis of molecular modeling design studies. The structure of the novel ureas was obtained from the pharmacological model, the parameters of which were determined from studies of the structure-activity relationship of pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Janovec, Ladislav, Kovacova, Eva, Semelakova, Martina, Kvakova, Monika, Kupka, Daniel, Jager, David, Kozurkova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398074/
https://www.ncbi.nlm.nih.gov/pubmed/34443446
http://dx.doi.org/10.3390/molecules26164860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398074/
https://www.ncbi.nlm.nih.gov/pubmed/34443446
http://dx.doi.org/10.3390/molecules26164860

Ejemplares similares