Cargando…
Synthesis of Novel Biologically Active Proflavine Ureas Designed on the Basis of Predicted Entropy Changes
A novel series of proflavine ureas, derivatives 11a–11i, were synthesized on the basis of molecular modeling design studies. The structure of the novel ureas was obtained from the pharmacological model, the parameters of which were determined from studies of the structure-activity relationship of pr...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398074/ https://www.ncbi.nlm.nih.gov/pubmed/34443446 http://dx.doi.org/10.3390/molecules26164860 |