Cargando…

Enhanced Bilosomal Properties Resulted in Optimum Pharmacological Effects by Increased Acidification Pathways

Introduction: Recent studies in our laboratory have shown that some bile acids, such as chenodeoxycholic acid (CDCA), can exert cellular protective effects when encapsulated with viable β-cells via anti-inflammatory and anti-oxidative stress mechanisms. However, to explore their full potential, form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mooranian, Armin, Foster, Thomas, Ionescu, Corina M., Walker, Daniel, Jones, Melissa, Wagle, Susbin Raj, Kovacevic, Bozica, Chester, Jacqueline, Johnston, Edan, Wong, Elaine, Atlas, Marcus D., Mikov, Momir, Al-Salami, Hani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398365/ https://www.ncbi.nlm.nih.gov/pubmed/34452145 http://dx.doi.org/10.3390/pharmaceutics13081184

Ejemplares similares

Advancements in Assessments of Bio-Tissue Engineering and Viable Cell Delivery Matrices Using Bile Acid-Based Pharmacological Biotechnologies
por: Mooranian, Armin, et al.
Publicado: (2021)

Reduced Cytokine Tumour Necrosis Factor by Pharmacological Intervention in a Preclinical Study
por: Mooranian, Armin, et al.
Publicado: (2022)

Probucol Pharmacological and Bio-Nanotechnological Effects on Surgically Transplanted Graft Due to Powerful Anti-Inflammatory, Anti-Fibrotic and Potential Bile Acid Modulatory Actions
por: Mooranian, Armin, et al.
Publicado: (2021)

A Review on Recent Advancement on Age-Related Hearing Loss: The Applications of Nanotechnology, Drug Pharmacology, and Biotechnology
por: Chester, Jacqueline, et al.
Publicado: (2021)

The Effects of Accelerated Temperature-Controlled Stability Systems on the Release Profile of Primary Bile Acid-Based Delivery Microcapsules
por: Mooranian, Armin, et al.
Publicado: (2021)

Chenodeoxycholic Acid Pharmacology in Biotechnology and Transplantable Pharmaceutical Applications for Tissue Delivery: An Acute Preclinical Study
por: Mooranian, Armin, et al.
Publicado: (2021)

Polyelectrolytes Formulated with Primary Unconjugated Bile Acid Optimised Pharmacology of Bio-Engineered Implant
por: Mooranian, Armin, et al.
Publicado: (2021)

Taurine Grafted Micro-Implants Improved Functions without Direct Dependency between Interleukin-6 and the Bile Acid Lithocholic Acid in Plasma
por: Mooranian, Armin, et al.
Publicado: (2022)

Artificial Cell Encapsulation for Biomaterials and Tissue Bio-Nanoengineering: History, Achievements, Limitations, and Future Work for Potential Clinical Applications and Transplantation
por: Mooranian, Armin, et al.
Publicado: (2021)

Biguanide Pharmaceutical Formulations and the Applications of Bile Acid-Based Nano Delivery in Chronic Medical Conditions
por: Jones, Melissa, et al.
Publicado: (2022)

Pharmacological Dose-Effect Profiles of Various Concentrations of Humanised Primary Bile Acid in Encapsulated Cells
por: Mooranian, Armin, et al.
Publicado: (2022)

Single-Cellular Biological Effects of Cholesterol-Catabolic Bile Acid-Based Nano/Micro Capsules as Anti-Inflammatory Cell Protective Systems
por: Mooranian, Armin, et al.
Publicado: (2022)

The Effect of Deoxycholic Acid on Chitosan-Enabled Matrices for Tissue Scaffolding and Injectable Nanogels
por: Kovacevic, Bozica, et al.
Publicado: (2022)

The Effects of Primary Unconjugated Bile Acids on Nanoencapsulated Pharmaceutical Formulation of Hydrophilic Drugs: Pharmacological Implications
por: Mooranian, Armin, et al.
Publicado: (2021)

Pharmacological and Biological Study of Microencapsulated Probucol-Secondary Bile Acid in a Diseased Mouse Model
por: Wagle, Susbin Raj, et al.
Publicado: (2021)

Micro-Nano formulation of bile-gut delivery: rheological, stability and cell survival, basal and maximum respiration studies
por: Wagle, Susbin Raj, et al.
Publicado: (2020)

Pharmacological and Advanced Cell Respiration Effects, Enhanced by Toxic Human-Bile Nano-Pharmaceuticals of Probucol Cell-Targeting Formulations
por: Wagle, Susbin Raj, et al.
Publicado: (2020)

Bile acid bio-nanoencapsulation improved drug targeted-delivery and pharmacological effects via cellular flux: 6-months diabetes preclinical study
por: Mooranian, Armin, et al.
Publicado: (2020)

A second-generation micro/nano capsules of an endogenous primary un-metabolised bile acid, stabilized by Eudragit-alginate complex with antioxidant compounds
por: Mooranian, Armin, et al.
Publicado: (2020)

Bio Micro-Nano Technologies of Antioxidants Optimised Their Pharmacological and Cellular Effects, ex vivo, in Pancreatic β-Cells
por: Mooranian, Armin, et al.
Publicado: (2020)

Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease
por: Lazarević, Slavica, et al.
Publicado: (2022)

Editorial: Pharmacokinetic evaluation and modeling of clinically significant drug metabolites, Volume II
por: Mikov, Momir, et al.
Publicado: (2023)

Bioaccumulation and biotransformation of simvastatin in probiotic bacteria: A step towards better understanding of drug-bile acids-microbiome interactions
por: Đanić, Maja, et al.
Publicado: (2023)

Pharmacological effects of novel microvesicles of basil, on blood glucose and the lipid profile: a preclinical study
por: Teofilovic, Branislava, et al.
Publicado: (2021)

An in vivo pharmacological study: Variation in tissue-accumulation for the drug probucol as the result of targeted microtechnology and matrix-acrylic acid optimization and stabilization techniques
por: Mooranian, Armin, et al.
Publicado: (2019)

Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study
por: Mooranian, Armin, et al.
Publicado: (2014)

Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics
por: Mooranian, Armin, et al.
Publicado: (2014)

Microencapsulation as a novel delivery method for the potential antidiabetic drug, Probucol
por: Mooranian, Armin, et al.
Publicado: (2014)

Probiotic Pre-treatment Reduces Gliclazide Permeation (ex vivo) in Healthy Rats but Increases It in Diabetic Rats to the Level Seen in Untreated Healthy Rats
por: Al-Salami, Hani, et al.
Publicado: (2008)

Inflammatory bowel disease: clinical aspects and treatments
por: Fakhoury, Marc, et al.
Publicado: (2014)

Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat
por: Lalić-Popović, Mladena, et al.
Publicado: (2013)

Diabetes and hypertension increase the placental and transcellular permeation of the lipophilic drug diazepam in pregnant women
por: Lalic-Popovic, Mladena, et al.
Publicado: (2013)

Transport and Biotransformation of Gliclazide and the Effect of Deoxycholic Acid in a Probiotic Bacteria Model
por: Ðanić, Maja, et al.
Publicado: (2019)

Pharmacological Applications of Bile Acids and Their Derivatives in the Treatment of Metabolic Syndrome
por: Ðanić, Maja, et al.
Publicado: (2018)

Bile Acids and Their Derivatives as Potential Modifiers of Drug Release and Pharmacokinetic Profiles
por: Pavlović, Nebojša, et al.
Publicado: (2018)

Influence of Bile Acids in Hydrogel Pharmaceutical Formulations on Dissolution Rate and Permeation of Clindamycin Hydrochloride
por: Pavlović, Nebojša, et al.
Publicado: (2022)

Abyssal oceanic circulation and acidification during the Middle Eocene Climatic Optimum (MECO)
por: Cornaggia, Flaminia, et al.
Publicado: (2020)

The Effect of Hypoalbuminemia on the Therapeutic Concentration and Dosage of Vancomycin in Critically Ill Septic Patients in Low-Resource Countries
por: Kovacevic, Tijana, et al.
Publicado: (2019)

Evaluation of Metformin Hydrochloride Tailoring Bilosomes as an Effective Transdermal Nanocarrier
por: Salem, Heba F, et al.
Publicado: (2022)

Novel Surface-Modified Bilosomes as Functional and Biocompatible Nanocarriers of Hybrid Compounds
por: Waglewska, Ewelina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ft7eejd2t0thvjh2aats35p1mj