Cargando…

Structure, Activity and Function of the NSD3 Protein Lysine Methyltransferase

NSD3 is one of six H3K36-specific lysine methyltransferases in metazoans, and the methylation of H3K36 is associated with active transcription. NSD3 is a member of the nuclear receptor-binding SET domain (NSD) family of histone methyltransferases together with NSD1 and NSD2, which generate mono- and...

Descripción completa

Detalles Bibliográficos
Autor principal:	Rathert, Philipp
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398374/ https://www.ncbi.nlm.nih.gov/pubmed/34440470 http://dx.doi.org/10.3390/life11080726

Ejemplares similares

The role of histone lysine methyltransferase NSD3 in cancer
por: Han, Xu, et al.
Publicado: (2018)

Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?
por: Krossa, Imène, et al.
Publicado: (2022)

NSD1: A Lysine Methyltransferase between Developmental Disorders and Cancer
por: Tauchmann, Samantha, et al.
Publicado: (2021)

The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate
por: Li, Yan, et al.
Publicado: (2009)

Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity
por: Jacques-Fricke, Bridget T., et al.
Publicado: (2014)

The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3
por: Wang, Chunmei, et al.
Publicado: (2017)

Structure, Activity, and Function of SETMAR Protein Lysine Methyltransferase
por: Tellier, Michael
Publicado: (2021)

In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L
por: Morishita, Masayo, et al.
Publicado: (2014)

Structure, Activity, and Function of the Protein Lysine Methyltransferase G9a
por: Poulard, Coralie, et al.
Publicado: (2021)

Understanding the Roles of the NSD Protein Methyltransferases in Head and Neck Squamous Cell Carcinoma
por: Murali, Madhavi, et al.
Publicado: (2022)

Covalent inhibition of NSD1 histone methyltransferase
por: Huang, Huang, et al.
Publicado: (2020)

Structure, Activity and Function of the MLL2 (KMT2B) Protein Lysine Methyltransferase
por: Klonou, Alexia, et al.
Publicado: (2021)

Structure, Activity and Function of the Dual Protein Lysine and Protein N-Terminal Methyltransferase METTL13
por: Jakobsson, Magnus E.
Publicado: (2021)

The Role of Methyltransferase NSD2 as a Potential Oncogene in Human Solid Tumors
por: Chen, Rui, et al.
Publicado: (2020)

Structure, activity and function of the lysine methyltransferase SETD5
por: Li, Mingyang, et al.
Publicado: (2023)

Histone methyltransferase NSD2 regulates apoptosis and chemosensitivity in osteosarcoma
por: He, Chao, et al.
Publicado: (2019)

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases
por: Li, Wanqiu, et al.
Publicado: (2020)

In silico derived small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor
por: Berardi, Andrea, et al.
Publicado: (2020)

Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion
por: Toubhans, Benoit, et al.
Publicado: (2023)

The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation
por: Khella, Mina S., et al.
Publicado: (2023)

Silencing of histone methyltransferase NSD3 reduces cell viability in osteosarcoma with induction of apoptosis
por: Liu, Zhiwei, et al.
Publicado: (2017)

Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation
por: Long, Xuehui, et al.
Publicado: (2019)

Clinicopathologic significance of protein lysine methyltransferases in cancer
por: Vougiouklakis, Theodore, et al.
Publicado: (2020)

Structure, Activity and Function of the Suv39h1 and Suv39h2 Protein Lysine Methyltransferases
por: Weirich, Sara, et al.
Publicado: (2021)

The SET-domain protein superfamily: protein lysine methyltransferases
por: Dillon, Shane C, et al.
Publicado: (2005)

SET/MYND Lysine Methyltransferases Regulate Gene Transcription and Protein Activity
por: Leinhart, Kristin, et al.
Publicado: (2011)

An Activating Mutation of the NSD2 Histone Methyltransferase Drives Oncogenic Reprogramming in Acute Lymphocytic Leukemia
por: Swaroop, Alok, et al.
Publicado: (2018)

Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer
por: Zhao, Li-hao, et al.
Publicado: (2021)

NSD3 keeps IRF3 active
por: Mino, Takashi, et al.
Publicado: (2017)

P1347: H3K36 HISTONE METHYLTRANSFERASE NSD3 FUNCTIONS AS A CRUCIAL EPIGENETIC REGULATOR OF ERYTHROPOIESIS
por: Shah, Arunim, et al.
Publicado: (2023)

Lysine Ethylation by Histone Lysine Methyltransferases
por: Al Temimi, Abbas H. K., et al.
Publicado: (2019)

The Structure, Activity, and Function of the SETD3 Protein Histidine Methyltransferase
por: Witecka, Apolonia, et al.
Publicado: (2021)

H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair
por: Shao, Rui, et al.
Publicado: (2021)

H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis
por: Li, Zhiming, et al.
Publicado: (2022)

The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence‐associated epigenomic remodeling
por: Tanaka, Hiroshi, et al.
Publicado: (2020)

Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
por: Gameiro, Steven F., et al.
Publicado: (2021)

Structure, Activity and Function of the Protein Arginine Methyltransferase 6
por: Gupta, Somlee, et al.
Publicado: (2021)

Structure, Activity and Function of the SETDB1 Protein Methyltransferase
por: Markouli, Mariam, et al.
Publicado: (2021)

NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons
por: Hamagami, Nicole, et al.
Publicado: (2023)

Correction: H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair
por: Shao, Rui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9sdrivnsci33eclc68mni1etqg