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Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually...

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Autores principales: Souto, Eliana B., Yoshida, Cristiana M. P., Leonardi, Gislaine R., Cano, Amanda, Sanchez-Lopez, Elena, Zielinska, Aleksandra, Viseras, César, Severino, Patricia, da Silva, Classius F., Barbosa, Raquel de M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398446/
https://www.ncbi.nlm.nih.gov/pubmed/34452160
http://dx.doi.org/10.3390/pharmaceutics13081199
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author Souto, Eliana B.
Yoshida, Cristiana M. P.
Leonardi, Gislaine R.
Cano, Amanda
Sanchez-Lopez, Elena
Zielinska, Aleksandra
Viseras, César
Severino, Patricia
da Silva, Classius F.
Barbosa, Raquel de M.
author_facet Souto, Eliana B.
Yoshida, Cristiana M. P.
Leonardi, Gislaine R.
Cano, Amanda
Sanchez-Lopez, Elena
Zielinska, Aleksandra
Viseras, César
Severino, Patricia
da Silva, Classius F.
Barbosa, Raquel de M.
author_sort Souto, Eliana B.
collection PubMed
description The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.
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spelling pubmed-83984462021-08-29 Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair Souto, Eliana B. Yoshida, Cristiana M. P. Leonardi, Gislaine R. Cano, Amanda Sanchez-Lopez, Elena Zielinska, Aleksandra Viseras, César Severino, Patricia da Silva, Classius F. Barbosa, Raquel de M. Pharmaceutics Review The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products. MDPI 2021-08-04 /pmc/articles/PMC8398446/ /pubmed/34452160 http://dx.doi.org/10.3390/pharmaceutics13081199 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Souto, Eliana B.
Yoshida, Cristiana M. P.
Leonardi, Gislaine R.
Cano, Amanda
Sanchez-Lopez, Elena
Zielinska, Aleksandra
Viseras, César
Severino, Patricia
da Silva, Classius F.
Barbosa, Raquel de M.
Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title_full Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title_fullStr Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title_full_unstemmed Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title_short Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair
title_sort lipid-polymeric films: composition, production and applications in wound healing and skin repair
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398446/
https://www.ncbi.nlm.nih.gov/pubmed/34452160
http://dx.doi.org/10.3390/pharmaceutics13081199
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