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New Insights into the Biology of the Emerging Tembusu Virus

Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its...

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Autores principales: Hamel, Rodolphe, Phanitchat, Thipruethai, Wichit, Sineewanlaya, Morales Vargas, Ronald Enrique, Jaroenpool, Jiraporn, Diagne, Cheikh Tidiane, Pompon, Julien, Missé, Dorothée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398659/
https://www.ncbi.nlm.nih.gov/pubmed/34451474
http://dx.doi.org/10.3390/pathogens10081010
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author Hamel, Rodolphe
Phanitchat, Thipruethai
Wichit, Sineewanlaya
Morales Vargas, Ronald Enrique
Jaroenpool, Jiraporn
Diagne, Cheikh Tidiane
Pompon, Julien
Missé, Dorothée
author_facet Hamel, Rodolphe
Phanitchat, Thipruethai
Wichit, Sineewanlaya
Morales Vargas, Ronald Enrique
Jaroenpool, Jiraporn
Diagne, Cheikh Tidiane
Pompon, Julien
Missé, Dorothée
author_sort Hamel, Rodolphe
collection PubMed
description Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host-virus interactions.
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spelling pubmed-83986592021-08-29 New Insights into the Biology of the Emerging Tembusu Virus Hamel, Rodolphe Phanitchat, Thipruethai Wichit, Sineewanlaya Morales Vargas, Ronald Enrique Jaroenpool, Jiraporn Diagne, Cheikh Tidiane Pompon, Julien Missé, Dorothée Pathogens Review Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host-virus interactions. MDPI 2021-08-10 /pmc/articles/PMC8398659/ /pubmed/34451474 http://dx.doi.org/10.3390/pathogens10081010 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hamel, Rodolphe
Phanitchat, Thipruethai
Wichit, Sineewanlaya
Morales Vargas, Ronald Enrique
Jaroenpool, Jiraporn
Diagne, Cheikh Tidiane
Pompon, Julien
Missé, Dorothée
New Insights into the Biology of the Emerging Tembusu Virus
title New Insights into the Biology of the Emerging Tembusu Virus
title_full New Insights into the Biology of the Emerging Tembusu Virus
title_fullStr New Insights into the Biology of the Emerging Tembusu Virus
title_full_unstemmed New Insights into the Biology of the Emerging Tembusu Virus
title_short New Insights into the Biology of the Emerging Tembusu Virus
title_sort new insights into the biology of the emerging tembusu virus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398659/
https://www.ncbi.nlm.nih.gov/pubmed/34451474
http://dx.doi.org/10.3390/pathogens10081010
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