Cargando…

Creatine Supplementation Upregulates mTORC1 Signaling and Markers of Synaptic Plasticity in the Dentate Gyrus While Ameliorating LPS-Induced Cognitive Impairment in Female Rats

Mild cognitive impairment (MCI) designates the boundary area between cognitive function in natural aging and dementia, and this is viewed as a therapeutic window to prevent the occurrence of dementia. The current study investigated the neurocognitive effects of oral creatine (Cr) supplementation in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Xuansong, Kelty, Taylor J., Kerr, Nathan R., Childs, Thomas E., Roberts, Michael D., Booth, Frank W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398736/ https://www.ncbi.nlm.nih.gov/pubmed/34444918 http://dx.doi.org/10.3390/nu13082758

Ejemplares similares

Selective breeding for physical inactivity produces cognitive deficits via altered hippocampal mitochondrial and synaptic function
por: Kerr, Nathan R., et al.
Publicado: (2023)

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
por: Ribeiro, Marcelle C., et al.
Publicado: (2018)

Short-Term Synaptic Plasticity in the Dentate Gyrus of Monkeys
por: Tamura, Ryoi, et al.
Publicado: (2011)

Acute Wheel-Running Increases Markers of Stress and Aversion-Related Signaling in the Basolateral Amygdala of Male Rats
por: Grigsby, Kolter B., et al.
Publicado: (2022)

Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission
por: McCabe, Matthew P, et al.
Publicado: (2020)

Enhanced Synaptic Connectivity in the Dentate Gyrus during Epileptiform Activity: Network Simulation
por: França, Keite Lira de Almeida, et al.
Publicado: (2013)

Effects of amitriptyline and fluoxetine on synaptic plasticity in the dentate gyrus of hippocampal formation in rats
por: Zarei, Ghasem, et al.
Publicado: (2014)

Exciting times for inhibition: GABAergic synaptic transmission in dentate gyrus interneuron networks
por: Ramaswamy, Srikanth
Publicado: (2015)

Synaptic Homeostasis and Allostasis in the Dentate Gyrus Caused by Inflammatory and Neuropathic Pain Conditions
por: Wang, Rui-Rui, et al.
Publicado: (2018)

The effects of hyperbilirubinaemia on synaptic plasticity in the dentate gyrus region of the rat hippocampus in vivo
por: Yang, Li, et al.
Publicado: (2019)

Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus
por: Sawchuk, Scott D., et al.
Publicado: (2020)

Altered synaptic plasticity of the longitudinal dentate gyrus network in noise-induced anxiety
por: Pak, Sojeong, et al.
Publicado: (2022)

Impaired synaptic transmission in dorsal dentate gyrus increases impulsive alcohol seeking
por: Nalberczak-Skóra, Maria, et al.
Publicado: (2022)

Upregulation of APP, ADAM10 and ADAM17 in the Denervated Mouse Dentate Gyrus
por: Del Turco, Domenico, et al.
Publicado: (2014)

Disruption of circadian timing increases synaptic inhibition and reduces cholinergic responsiveness in the dentate gyrus
por: McMartin, Laura, et al.
Publicado: (2021)

Lentiviral-Mediated Overexpression of the 18 kDa Translocator Protein (TSPO) in the Hippocampal Dentate Gyrus Ameliorates LPS-Induced Cognitive Impairment in Mice
por: Wang, Wei, et al.
Publicado: (2016)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Reassessing pattern separation in the dentate gyrus
por: Santoro, Adam
Publicado: (2013)

Microelastic mapping of the rat dentate gyrus
por: Luque, Tomás, et al.
Publicado: (2016)

Sampling the Mouse Hippocampal Dentate Gyrus
por: Basler, Lisa, et al.
Publicado: (2017)

Moderate Traumatic Brain Injury Causes Acute Dendritic and Synaptic Degeneration in the Hippocampal Dentate Gyrus
por: Gao, Xiang, et al.
Publicado: (2011)

Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy
por: Alonso-Nanclares, Lidia, et al.
Publicado: (2013)

Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat
por: Smidak, Roman, et al.
Publicado: (2017)

R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity
por: Shanmugasundaram, Bharanidharan, et al.
Publicado: (2017)

GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory
por: Liu, Enjie, et al.
Publicado: (2017)

Neuroligin-3 Regulates Excitatory Synaptic Transmission and EPSP-Spike Coupling in the Dentate Gyrus In Vivo
por: Muellerleile, Julia, et al.
Publicado: (2021)

In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice
por: Rodríguez-Matellán, Alberto, et al.
Publicado: (2020)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

Rapamycin Ameliorates Inflammation and Fibrosis in the Early Phase of Cirrhotic Portal Hypertension in Rats through Inhibition of mTORC1 but Not mTORC2
por: Wang, Weijie, et al.
Publicado: (2014)

Functional circuits of new neurons in the dentate gyrus
por: Vivar, Carmen, et al.
Publicado: (2013)

Adult neurogenesis modifies excitability of the dentate gyrus
por: Ikrar, Taruna, et al.
Publicado: (2013)

Immature Dentate Gyrus: An Endophenotype of Neuropsychiatric Disorders
por: Hagihara, Hideo, et al.
Publicado: (2013)

The Role of Dentate Gyrus Neurogenesis in Neuropsychiatric Disorders
por: García-Fuster, M. Julia, et al.
Publicado: (2013)

The dentate gyrus in depression: directions for future research
por: Nuninga, Jasper O., et al.
Publicado: (2020)

Differential vulnerability of the dentate gyrus to tauopathies in dementias
por: Kawles, Allegra, et al.
Publicado: (2023)

Strain-Dependent Variations in Spatial Learning and in Hippocampal Synaptic Plasticity in the Dentate Gyrus Of Freely Behaving Rats
por: Manahan-Vaughan, Denise, et al.
Publicado: (2011)

Chronic Social Stress Affects Synaptic Maturation of Newly Generated Neurons in the Adult Mouse Dentate Gyrus
por: Chen, Chien-Chung, et al.
Publicado: (2015)

Replacement of Asymmetric Synaptic Profiles in the Molecular Layer of Dentate Gyrus Following Cycloheximide in the Pilocarpine Model in Rats
por: Bittencourt, Simone, et al.
Publicado: (2015)

Somatostatin-positive interneurons in the dentate gyrus of mice provide local- and long-range septal synaptic inhibition
por: Yuan, Mei, et al.
Publicado: (2017)

Effects of Hypericum scabrum extract on dentate gyrus synaptic plasticity in high fat diet-fed rats
por: Omidi, Ghazaleh, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bc5s5i0jgv0cv981lqc71hvh35