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Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data

The success of risk-stratified approaches in improving population-based breast cancer screening programs depends in no small part on women’s buy-in. Fear of genetic discrimination (GD) could be a potential barrier to genetic testing uptake as part of risk assessment. Thus, the objective of this stud...

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Autores principales: Alarie, Samuel, Hagan, Julie, Dalpé, Gratien, Faraji, Sina, Mbuya-Bienge, Cynthia, Nabi, Hermann, Pashayan, Nora, Brooks, Jennifer D., Dorval, Michel, Chiquette, Jocelyne, Eloy, Laurence, Turgeon, Annie, Lambert-Côté, Laurence, Paquette, Jean-Sébastien, Walker, Meghan J., Lapointe, Julie, Granados Moreno, Palmira, Blackmore, Kristina, Wolfson, Michael, Broeders, Mireille, Knoppers, Bartha M., Chiarelli, Anna M., Simard, Jacques, Joly, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398750/
https://www.ncbi.nlm.nih.gov/pubmed/34442372
http://dx.doi.org/10.3390/jpm11080726
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author Alarie, Samuel
Hagan, Julie
Dalpé, Gratien
Faraji, Sina
Mbuya-Bienge, Cynthia
Nabi, Hermann
Pashayan, Nora
Brooks, Jennifer D.
Dorval, Michel
Chiquette, Jocelyne
Eloy, Laurence
Turgeon, Annie
Lambert-Côté, Laurence
Paquette, Jean-Sébastien
Walker, Meghan J.
Lapointe, Julie
Granados Moreno, Palmira
Blackmore, Kristina
Wolfson, Michael
Broeders, Mireille
Knoppers, Bartha M.
Chiarelli, Anna M.
Simard, Jacques
Joly, Yann
author_facet Alarie, Samuel
Hagan, Julie
Dalpé, Gratien
Faraji, Sina
Mbuya-Bienge, Cynthia
Nabi, Hermann
Pashayan, Nora
Brooks, Jennifer D.
Dorval, Michel
Chiquette, Jocelyne
Eloy, Laurence
Turgeon, Annie
Lambert-Côté, Laurence
Paquette, Jean-Sébastien
Walker, Meghan J.
Lapointe, Julie
Granados Moreno, Palmira
Blackmore, Kristina
Wolfson, Michael
Broeders, Mireille
Knoppers, Bartha M.
Chiarelli, Anna M.
Simard, Jacques
Joly, Yann
author_sort Alarie, Samuel
collection PubMed
description The success of risk-stratified approaches in improving population-based breast cancer screening programs depends in no small part on women’s buy-in. Fear of genetic discrimination (GD) could be a potential barrier to genetic testing uptake as part of risk assessment. Thus, the objective of this study was twofold. First, to evaluate Canadian women’s knowledge of the legislative context governing GD. Second, to assess their concerns about the possible use of breast cancer risk levels by insurance companies or employers. We use a cross-sectional survey of 4293 (age: 30–69) women, conducted in four Canadian provinces (Alberta, British Colombia, Ontario and Québec). Canadian women’s knowledge of the regulatory framework for GD is relatively limited, with some gaps and misconceptions noted. About a third (34.7%) of the participants had a lot of concerns about the use of their health information by employers or insurers; another third had some concerns (31.9%), while 20% had no concerns. There is a need to further educate and inform the Canadian public about GD and the legal protections that exist to prevent it. Enhanced knowledge could facilitate the implementation and uptake of risk prediction informed by genetic factors, such as the risk-stratified approach to breast cancer screening that includes risk levels.
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spelling pubmed-83987502021-08-29 Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data Alarie, Samuel Hagan, Julie Dalpé, Gratien Faraji, Sina Mbuya-Bienge, Cynthia Nabi, Hermann Pashayan, Nora Brooks, Jennifer D. Dorval, Michel Chiquette, Jocelyne Eloy, Laurence Turgeon, Annie Lambert-Côté, Laurence Paquette, Jean-Sébastien Walker, Meghan J. Lapointe, Julie Granados Moreno, Palmira Blackmore, Kristina Wolfson, Michael Broeders, Mireille Knoppers, Bartha M. Chiarelli, Anna M. Simard, Jacques Joly, Yann J Pers Med Article The success of risk-stratified approaches in improving population-based breast cancer screening programs depends in no small part on women’s buy-in. Fear of genetic discrimination (GD) could be a potential barrier to genetic testing uptake as part of risk assessment. Thus, the objective of this study was twofold. First, to evaluate Canadian women’s knowledge of the legislative context governing GD. Second, to assess their concerns about the possible use of breast cancer risk levels by insurance companies or employers. We use a cross-sectional survey of 4293 (age: 30–69) women, conducted in four Canadian provinces (Alberta, British Colombia, Ontario and Québec). Canadian women’s knowledge of the regulatory framework for GD is relatively limited, with some gaps and misconceptions noted. About a third (34.7%) of the participants had a lot of concerns about the use of their health information by employers or insurers; another third had some concerns (31.9%), while 20% had no concerns. There is a need to further educate and inform the Canadian public about GD and the legal protections that exist to prevent it. Enhanced knowledge could facilitate the implementation and uptake of risk prediction informed by genetic factors, such as the risk-stratified approach to breast cancer screening that includes risk levels. MDPI 2021-07-27 /pmc/articles/PMC8398750/ /pubmed/34442372 http://dx.doi.org/10.3390/jpm11080726 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alarie, Samuel
Hagan, Julie
Dalpé, Gratien
Faraji, Sina
Mbuya-Bienge, Cynthia
Nabi, Hermann
Pashayan, Nora
Brooks, Jennifer D.
Dorval, Michel
Chiquette, Jocelyne
Eloy, Laurence
Turgeon, Annie
Lambert-Côté, Laurence
Paquette, Jean-Sébastien
Walker, Meghan J.
Lapointe, Julie
Granados Moreno, Palmira
Blackmore, Kristina
Wolfson, Michael
Broeders, Mireille
Knoppers, Bartha M.
Chiarelli, Anna M.
Simard, Jacques
Joly, Yann
Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title_full Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title_fullStr Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title_full_unstemmed Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title_short Risk-Stratified Approach to Breast Cancer Screening in Canada: Women’s Knowledge of the Legislative Context and Concerns about Discrimination from Genetic and Other Predictive Health Data
title_sort risk-stratified approach to breast cancer screening in canada: women’s knowledge of the legislative context and concerns about discrimination from genetic and other predictive health data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398750/
https://www.ncbi.nlm.nih.gov/pubmed/34442372
http://dx.doi.org/10.3390/jpm11080726
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