Aptamers with Self-Loading Drug Payload and pH-Controlled Drug Release for Targeted Chemotherapy

Doxorubicin (DOX) is a common anti-tumor drug that binds to DNA or RNA via non-covalent intercalation between G-C sequences. As a therapeutic agent, DOX has been used to form aptamer–drug conjugates for targeted cancer therapy in vitro and in vivo. To improve the therapeutic potential of aptamer–DOX...

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Detalles Bibliográficos
Autores principales: Zeng, Zihua, Qi, Jianjun, Wan, Quanyuan, Zu, Youli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398837/
https://www.ncbi.nlm.nih.gov/pubmed/34452182
http://dx.doi.org/10.3390/pharmaceutics13081221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398837/
https://www.ncbi.nlm.nih.gov/pubmed/34452182
http://dx.doi.org/10.3390/pharmaceutics13081221

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