Oxidative Stress and the Neurovascular Unit

The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each other that they are considered as a single fun...

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Detalles Bibliográficos
Autores principales: Rinaldi, Carmela, Donato, Luigi, Alibrandi, Simona, Scimone, Concetta, D’Angelo, Rosalia, Sidoti, Antonina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398978/
https://www.ncbi.nlm.nih.gov/pubmed/34440511
http://dx.doi.org/10.3390/life11080767
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author Rinaldi, Carmela
Donato, Luigi
Alibrandi, Simona
Scimone, Concetta
D’Angelo, Rosalia
Sidoti, Antonina
author_facet Rinaldi, Carmela
Donato, Luigi
Alibrandi, Simona
Scimone, Concetta
D’Angelo, Rosalia
Sidoti, Antonina
author_sort Rinaldi, Carmela
collection PubMed
description The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each other that they are considered as a single functioning unit. For this reason, even slight disturbances in the NVU could severely affect brain homeostasis and health. In this review, we aim to describe the current state of knowledge concerning the role of oxidative stress on the neurovascular unit and the role of a single cell type in the NVU crosstalk.
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spelling pubmed-83989782021-08-29 Oxidative Stress and the Neurovascular Unit Rinaldi, Carmela Donato, Luigi Alibrandi, Simona Scimone, Concetta D’Angelo, Rosalia Sidoti, Antonina Life (Basel) Review The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each other that they are considered as a single functioning unit. For this reason, even slight disturbances in the NVU could severely affect brain homeostasis and health. In this review, we aim to describe the current state of knowledge concerning the role of oxidative stress on the neurovascular unit and the role of a single cell type in the NVU crosstalk. MDPI 2021-07-29 /pmc/articles/PMC8398978/ /pubmed/34440511 http://dx.doi.org/10.3390/life11080767 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rinaldi, Carmela
Donato, Luigi
Alibrandi, Simona
Scimone, Concetta
D’Angelo, Rosalia
Sidoti, Antonina
Oxidative Stress and the Neurovascular Unit
title Oxidative Stress and the Neurovascular Unit
title_full Oxidative Stress and the Neurovascular Unit
title_fullStr Oxidative Stress and the Neurovascular Unit
title_full_unstemmed Oxidative Stress and the Neurovascular Unit
title_short Oxidative Stress and the Neurovascular Unit
title_sort oxidative stress and the neurovascular unit
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398978/
https://www.ncbi.nlm.nih.gov/pubmed/34440511
http://dx.doi.org/10.3390/life11080767
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