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LATE–a novel sensitive cell-based assay for the study of CRISPR/Cas9-related long-term adverse treatment effects

Since the introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), genome editing has been broadly applied in basic research and applied biotechnology, whereas translation into clinical testing has raised safety concerns. Indeed, although...

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Detalles Bibliográficos
Autores principales: Głów, Dawid, Meyer, Simon, García Roldán, Irene, Akingunsade, Lara Marie, Riecken, Kristoffer, Fehse, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399046/
https://www.ncbi.nlm.nih.gov/pubmed/34485609
http://dx.doi.org/10.1016/j.omtm.2021.07.004