Cargando…
LATE–a novel sensitive cell-based assay for the study of CRISPR/Cas9-related long-term adverse treatment effects
Since the introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), genome editing has been broadly applied in basic research and applied biotechnology, whereas translation into clinical testing has raised safety concerns. Indeed, although...
Autores principales: | Głów, Dawid, Meyer, Simon, García Roldán, Irene, Akingunsade, Lara Marie, Riecken, Kristoffer, Fehse, Boris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399046/ https://www.ncbi.nlm.nih.gov/pubmed/34485609 http://dx.doi.org/10.1016/j.omtm.2021.07.004 |
Ejemplares similares
-
How to package and SEND mRNA: a novel “humanized” vector system based on endogenous retroviruses
por: Riecken, Kristoffer, et al.
Publicado: (2021) -
Deep Characterization and Comparison of Different Retrovirus-like Particles Preloaded with CRISPR/Cas9 RNPs
por: Wichmann, Max, et al.
Publicado: (2023) -
CRISPR-to-Kill (C2K)–Employing the Bacterial Immune System to Kill Cancer Cells
por: Głów, Dawid, et al.
Publicado: (2021) -
Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
por: Schwarze, Lea Isabell, et al.
Publicado: (2021) -
Correction: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
por: Schwarze, Lea Isabell, et al.
Publicado: (2022)