Lipid Transporters Beam Signals from Cell Membranes

Lipid composition in cellular membranes plays an important role in maintaining the structural integrity of cells and in regulating cellular signaling that controls functions of both membrane-anchored and cytoplasmic proteins. ATP-dependent ABC and P4-ATPase lipid transporters, two integral membrane...

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Autores principales: Ristovski, Miliça, Farhat, Danny, Bancud, Shelly Ellaine M., Lee, Jyh-Yeuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399137/
https://www.ncbi.nlm.nih.gov/pubmed/34436325
http://dx.doi.org/10.3390/membranes11080562
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author Ristovski, Miliça
Farhat, Danny
Bancud, Shelly Ellaine M.
Lee, Jyh-Yeuan
author_facet Ristovski, Miliça
Farhat, Danny
Bancud, Shelly Ellaine M.
Lee, Jyh-Yeuan
author_sort Ristovski, Miliça
collection PubMed
description Lipid composition in cellular membranes plays an important role in maintaining the structural integrity of cells and in regulating cellular signaling that controls functions of both membrane-anchored and cytoplasmic proteins. ATP-dependent ABC and P4-ATPase lipid transporters, two integral membrane proteins, are known to contribute to lipid translocation across the lipid bilayers on the cellular membranes. In this review, we will highlight current knowledge about the role of cholesterol and phospholipids of cellular membranes in regulating cell signaling and how lipid transporters participate this process.
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spelling pubmed-83991372021-08-29 Lipid Transporters Beam Signals from Cell Membranes Ristovski, Miliça Farhat, Danny Bancud, Shelly Ellaine M. Lee, Jyh-Yeuan Membranes (Basel) Review Lipid composition in cellular membranes plays an important role in maintaining the structural integrity of cells and in regulating cellular signaling that controls functions of both membrane-anchored and cytoplasmic proteins. ATP-dependent ABC and P4-ATPase lipid transporters, two integral membrane proteins, are known to contribute to lipid translocation across the lipid bilayers on the cellular membranes. In this review, we will highlight current knowledge about the role of cholesterol and phospholipids of cellular membranes in regulating cell signaling and how lipid transporters participate this process. MDPI 2021-07-26 /pmc/articles/PMC8399137/ /pubmed/34436325 http://dx.doi.org/10.3390/membranes11080562 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ristovski, Miliça
Farhat, Danny
Bancud, Shelly Ellaine M.
Lee, Jyh-Yeuan
Lipid Transporters Beam Signals from Cell Membranes
title Lipid Transporters Beam Signals from Cell Membranes
title_full Lipid Transporters Beam Signals from Cell Membranes
title_fullStr Lipid Transporters Beam Signals from Cell Membranes
title_full_unstemmed Lipid Transporters Beam Signals from Cell Membranes
title_short Lipid Transporters Beam Signals from Cell Membranes
title_sort lipid transporters beam signals from cell membranes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399137/
https://www.ncbi.nlm.nih.gov/pubmed/34436325
http://dx.doi.org/10.3390/membranes11080562
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AT bancudshellyellainem lipidtransportersbeamsignalsfromcellmembranes
AT leejyhyeuan lipidtransportersbeamsignalsfromcellmembranes

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