Cargando…

The Leucine Catabolite and Dietary Supplement β-Hydroxy-β-Methyl Butyrate (HMB) as an Epigenetic Regulator in Muscle Progenitor Cells

β-Hydroxy-β-Methyl Butyrate (HMB) is a natural catabolite of leucine deemed to play a role in amino acid signaling and the maintenance of lean muscle mass. Accordingly, HMB is used as a dietary supplement by sportsmen and has shown some clinical effectiveness in preventing muscle wasting in cancer a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavallucci, Virve, Pani, Giovambattista
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399199/ https://www.ncbi.nlm.nih.gov/pubmed/34436453 http://dx.doi.org/10.3390/metabo11080512

Ejemplares similares

The influence of dietary supplementation with the leucine metabolite β-hydroxy-β-methylbutyrate (HMB) on the chemotaxis, phagocytosis and respiratory burst of peripheral blood granulocytes and monocytes in calves
por: Wójcik, Roman, et al.
Publicado: (2020)

Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice
por: Vallejo, Julian, et al.
Publicado: (2016)

Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes
por: Manzano, Manuel, et al.
Publicado: (2023)

Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice
por: Ikeda, Kazuki, et al.
Publicado: (2021)

Randomized Clinical Trial: Effects of β-Hydroxy-β-Methylbutyrate (HMB)-Enriched vs. HMB-Free Oral Nutritional Supplementation in Malnourished Cirrhotic Patients
por: Espina, Silvia, et al.
Publicado: (2022)

Acute anabolic response to β-hydroxy-β-methylbutyrate (HMB)-free acid supplementation following heavy resistance exercise
por: Townsend, JR, et al.
Publicado: (2014)

The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes
por: Sarubbo, Fiorella, et al.
Publicado: (2022)

Supplementation with the Leucine Metabolite β-hydroxy-β-methylbutyrate (HMB) does not Improve Resistance Exercise-Induced Changes in Body Composition or Strength in Young Subjects: A Systematic Review and Meta-Analysis
por: Jakubowski, Josephine S., et al.
Publicado: (2020)

β-Hydroxy-β-Methylbutyrate (HMB) Promotes Neurite Outgrowth in Neuro2a Cells
por: Salto, Rafael, et al.
Publicado: (2015)

Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB)
por: Szcześniak, Katarzyna A., et al.
Publicado: (2016)

Suppression of protein degradation by leucine requires its conversion to β-hydroxy-β-methyl butyrate in C2C12 myotubes
por: Duan, Yehui, et al.
Publicado: (2019)

Effects of β‐hydroxy β‐methylbutyrate (HMB) supplementation on muscle mass, function, and other outcomes in patients with cancer: a systematic review
por: Prado, Carla M., et al.
Publicado: (2022)

β-Hydroxy-β-Methylbutyrate (HMB) Normalizes Dexamethasone-Induced Autophagy-Lysosomal Pathway in Skeletal Muscle
por: Girón, María D., et al.
Publicado: (2015)

Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
por: Lin, Ziru, et al.
Publicado: (2022)

An umbrella review of systematic reviews of β‐hydroxy‐β‐methyl butyrate supplementation in ageing and clinical practice
por: Phillips, Stuart M., et al.
Publicado: (2022)

Equivalent Hypertrophy and Strength Gains in β-Hydroxy-β-Methylbutyrate- or Leucine-supplemented Men
por: JAKUBOWSKI, JOSEPHINE S., et al.
Publicado: (2019)

Health Benefits of β-Hydroxy-β-Methylbutyrate (HMB) Supplementation in Addition to Physical Exercise in Older Adults: A Systematic Review with Meta-Analysis
por: Courel-Ibáñez, Javier, et al.
Publicado: (2019)

The addition of β-Hydroxy β-Methylbutyrate (HMB) to creatine monohydrate supplementation does not improve anthropometric and performance maintenance across a collegiate rugby season
por: Mangine, Gerald T., et al.
Publicado: (2020)

The Effects of β-Hydroxy-β-Methylbutyrate (HMB) on Chemotaxis, Phagocytosis, and Oxidative Burst of Peripheral Blood Granulocytes and Monocytes in Goats
por: Wójcik, Roman, et al.
Publicado: (2019)

β-Hydroxy-β-Methylbutyrate (HMB) Supplementation Prevents Bone Loss during Pregnancy—Novel Evidence from a Spiny Mouse (Acomys cahirinus) Model
por: Tomaszewska, Ewa, et al.
Publicado: (2021)

Effects of combined β-hydroxy-β-methylbutyrate (HMB) and whey protein ingestion on symptoms of eccentric exercise-induced muscle damage
por: Shirato, Minayuki, et al.
Publicado: (2016)

Fourier Transform Infrared Microspectroscopy Combined with Principal Component Analysis and Artificial Neural Networks for the Study of the Effect of β-Hydroxy-β-Methylbutyrate (HMB) Supplementation on Articular Cartilage
por: Świetlicka, Izabela, et al.
Publicado: (2021)

β-Hydroxy-β-methylbutyrate (HMB) supplementation and functional outcomes in multi-trauma patients: a study protocol for a pilot randomised clinical trial (BOOST trial)
por: Wittholz, Kym, et al.
Publicado: (2022)

Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring
por: Tatara, Marcin R, et al.
Publicado: (2012)

The Effect of 12 Weeks of β-Hydroxy-β-Methyl-Butyrate Supplementation after Liver Transplantation: A Pilot Randomized Controlled Study
por: Lattanzi, Barbara, et al.
Publicado: (2019)

Femoral µCT Analysis, Mechanical Testing and Immunolocalization of Bone Proteins in β-Hydroxy β-Methylbutyrate (HMB) Supplemented Spiny Mouse in a Model of Pregnancy and Lactation-Associated Osteoporosis
por: Tomaszewska, Ewa, et al.
Publicado: (2021)

β-Hydroxy-β-methyl Butyrate Regulates the Lipid Metabolism, Mitochondrial Function, and Fat Browning of Adipocytes
por: Duan, Geyan, et al.
Publicado: (2023)

Dietary Beta-Hydroxy Beta-Methyl Butyrate Supplementation Alleviates Liver Injury in Lipopolysaccharide-Challenged Piglets
por: Duan, Yehui, et al.
Publicado: (2021)

Net Absorption and Metabolism of β-Hydroxy- β-Methyl Butyrate during Late Gestation in a Pig Model
por: Hu, Liang, et al.
Publicado: (2020)

Effects of the Combination of β-Hydroxy-β-Methyl Butyrate and R(+) Lipoic Acid in a Cellular Model of Sarcopenia
por: Mannelli, Lorenzo Di Cesare, et al.
Publicado: (2020)

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3
por: Higuchi, Kei, et al.
Publicado: (2021)

Leucine and HMB Differentially Modulate Proteasome System in Skeletal Muscle under Different Sarcopenic Conditions
por: Baptista, Igor L., et al.
Publicado: (2013)

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism
por: Wilkinson, D J, et al.
Publicado: (2013)

Discrepancies in publications related to HMB-FA and ATP supplementation
por: Gentles, Jeremy A., et al.
Publicado: (2017)

Effects of β-hydroxy-β-methylbutyrate (HMB) supplementation in addition to multicomponent exercise in adults older than 70 years living in nursing homes, a cluster randomized placebo-controlled trial: the HEAL study protocol
por: Courel-Ibáñez, Javier, et al.
Publicado: (2019)

Correction: Leucine and HMB Differentially Modulate Proteasome System in Skeletal Muscle under Different Sarcopenic Conditions
por: Baptista, Igor L., et al.
Publicado: (2013)

Mechanism of Action and the Effect of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Different Types of Physical Performance - A Systematic Review
por: Kaczka, Piotr, et al.
Publicado: (2019)

International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)
por: Wilson, Jacob M, et al.
Publicado: (2013)

L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy
por: Mobley, Christopher Brooks, et al.
Publicado: (2014)

Long-Term Effect of Combination of Creatine Monohydrate Plus β-Hydroxy β-Methylbutyrate (HMB) on Exercise-Induced Muscle Damage and Anabolic/Catabolic Hormones in Elite Male Endurance Athletes
por: Fernández-Landa, Julen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qcmcpignkb2j1t8v9hv365kia0