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Synthesis, In Silico and In Vitro Evaluation of Antimicrobial and Toxicity Features of New 4-[(4-Chlorophenyl)sulfonyl]benzoic Acid Derivatives

The multi-step synthesis, physico-chemical characterization, and biological activity of novel valine-derived compounds, i.e., N-acyl-α-amino acids, 1,3-oxazol-5(4H)-ones, N-acyl-α-amino ketones, and 1,3-oxazoles derivatives, bearing a 4-[(4-chlorophenyl)sulfonyl]phenyl moiety are reported here. The...

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Detalles Bibliográficos
Autores principales: Apostol, Theodora-Venera, Chifiriuc, Mariana Carmen, Draghici, Constantin, Socea, Laura-Ileana, Marutescu, Luminita Gabriela, Olaru, Octavian Tudorel, Nitulescu, George Mihai, Pahontu, Elena Mihaela, Saramet, Gabriel, Barbuceanu, Stefania-Felicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399259/
https://www.ncbi.nlm.nih.gov/pubmed/34443693
http://dx.doi.org/10.3390/molecules26165107