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Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion
Hydrophobic derivatives of polysaccharides possess an amphiphilic behavior and are widely used as rheological modifiers, selective sorbents, and stabilizers for compositions intended for various applications. In this work, we studied the mechanochemical reactions of chitosan alkylation when interact...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399264/ https://www.ncbi.nlm.nih.gov/pubmed/34451348 http://dx.doi.org/10.3390/polym13162807 |
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author | Akopova, Tatiana A. Demina, Tatiana S. Khavpachev, Mukhamed A. Popyrina, Tatiana N. Grachev, Andrey V. Ivanov, Pavel L. Zelenetskii, Alexander N. |
author_facet | Akopova, Tatiana A. Demina, Tatiana S. Khavpachev, Mukhamed A. Popyrina, Tatiana N. Grachev, Andrey V. Ivanov, Pavel L. Zelenetskii, Alexander N. |
author_sort | Akopova, Tatiana A. |
collection | PubMed |
description | Hydrophobic derivatives of polysaccharides possess an amphiphilic behavior and are widely used as rheological modifiers, selective sorbents, and stabilizers for compositions intended for various applications. In this work, we studied the mechanochemical reactions of chitosan alkylation when interacting with docosylglycidyl and hexadecylglycidyl ethers in the absence of solvents at shear deformation in a pilot twin-screw extruder. The chemical structure and physical properties of the obtained derivatives were characterized by elemental analysis, FT-IR spectroscopy, dynamic light scattering, scanning electron microscopy, and mechanical tests. According to calculations for products soluble in aqueous media, it was possible to introduce about 5–12 hydrophobic fragments per chitosan macromolecule with a degree of polymerization of 500–2000. The length of the carbon chain of the alkyl substituent significantly affects its reactivity under the chosen conditions of mechanochemical synthesis. It was shown that modification disturbs the packing ability of the macromolecules, resulting in an increase of plasticity and drop in the elastic modulus of the film made from the hydrophobically modified chitosan samples. |
format | Online Article Text |
id | pubmed-8399264 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83992642021-08-29 Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion Akopova, Tatiana A. Demina, Tatiana S. Khavpachev, Mukhamed A. Popyrina, Tatiana N. Grachev, Andrey V. Ivanov, Pavel L. Zelenetskii, Alexander N. Polymers (Basel) Article Hydrophobic derivatives of polysaccharides possess an amphiphilic behavior and are widely used as rheological modifiers, selective sorbents, and stabilizers for compositions intended for various applications. In this work, we studied the mechanochemical reactions of chitosan alkylation when interacting with docosylglycidyl and hexadecylglycidyl ethers in the absence of solvents at shear deformation in a pilot twin-screw extruder. The chemical structure and physical properties of the obtained derivatives were characterized by elemental analysis, FT-IR spectroscopy, dynamic light scattering, scanning electron microscopy, and mechanical tests. According to calculations for products soluble in aqueous media, it was possible to introduce about 5–12 hydrophobic fragments per chitosan macromolecule with a degree of polymerization of 500–2000. The length of the carbon chain of the alkyl substituent significantly affects its reactivity under the chosen conditions of mechanochemical synthesis. It was shown that modification disturbs the packing ability of the macromolecules, resulting in an increase of plasticity and drop in the elastic modulus of the film made from the hydrophobically modified chitosan samples. MDPI 2021-08-21 /pmc/articles/PMC8399264/ /pubmed/34451348 http://dx.doi.org/10.3390/polym13162807 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Akopova, Tatiana A. Demina, Tatiana S. Khavpachev, Mukhamed A. Popyrina, Tatiana N. Grachev, Andrey V. Ivanov, Pavel L. Zelenetskii, Alexander N. Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title | Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title_full | Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title_fullStr | Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title_full_unstemmed | Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title_short | Hydrophobic Modification of Chitosan via Reactive Solvent-Free Extrusion |
title_sort | hydrophobic modification of chitosan via reactive solvent-free extrusion |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399264/ https://www.ncbi.nlm.nih.gov/pubmed/34451348 http://dx.doi.org/10.3390/polym13162807 |
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