Cargando…

Modulation of the Primary Astrocyte-Enriched Cultures’ Oxylipin Profiles Reduces Neurotoxicity

Recently, manipulations with reactive astrocytes have been viewed as a new therapeutic approach that will enable the development of treatments for acute brain injuries and neurodegenerative diseases. Astrocytes can release several substances, which may exert neurotoxic or neuroprotective effects, bu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guryleva, Mariia V., Chistyakov, Dmitry V., Lopachev, Alexander V., Goriainov, Sergei V., Astakhova, Alina A., Timoshina, Yulia A., Khutorova, Anastasiya V., Fedorova, Tatiana N., Sergeeva, Marina G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399552/ https://www.ncbi.nlm.nih.gov/pubmed/34436439 http://dx.doi.org/10.3390/metabo11080498

Ejemplares similares

High Glucose Shifts the Oxylipin Profiles in the Astrocytes towards Pro-Inflammatory States
por: Chistyakov, Dmitry V., et al.
Publicado: (2021)

Cellular Model of Endotoxin Tolerance in Astrocytes: Role of Interleukin 10 and Oxylipins
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Oxylipin Profiles in Plasma of Patients with Wilson’s Disease
por: Azbukina, Nadezhda V., et al.
Publicado: (2020)

Oxylipin Profiles as Functional Characteristics of Acute Inflammatory Responses in Astrocytes Pre-Treated with IL-4, IL-10, or LPS
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Multi-Omics Approach Points to the Importance of Oxylipins Metabolism in Early-Stage Breast Cancer
por: Chistyakov, Dmitry V., et al.
Publicado: (2022)

Sex-Mediated Differences in LPS Induced Alterations of TNFα, IL-10 Expression, and Prostaglandin Synthesis in Primary Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

Inhibitor of Hyaluronic Acid Synthesis 4-Methylumbelliferone as an Anti-Inflammatory Modulator of LPS-Mediated Astrocyte Responses
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Rosiglitazone as a Modulator of TLR4 and TLR3 Signaling Pathways in Rat Primary Neurons and Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

An overview of the pathogenic mechanisms involved in severe cases of COVID-19 infection, and the proposal of salicyl-carnosine as a potential drug for its treatment
por: Lopachev, Alexander V., et al.
Publicado: (2020)

Ouabain-Induced Gene Expression Changes in Human iPSC-Derived Neuron Culture Expressing Dopamine and cAMP-Regulated Phosphoprotein 32 and GABA Receptors
por: Lopachev, Alexander V., et al.
Publicado: (2021)

Inflammation in Dry Eye Syndrome: Identification and Targeting of Oxylipin-Mediated Mechanisms
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Investigation of the Role of PUFA Metabolism in Breast Cancer Using a Rank-Based Random Forest Algorithm
por: Guryleva, Mariia V., et al.
Publicado: (2022)

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization
por: Astakhova, Alina, et al.
Publicado: (2019)

Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma
por: Azbukina, Nadezhda V., et al.
Publicado: (2021)

Intracerebroventricular injection of ouabain causes mania-like behavior in mice through D2 receptor activation
por: Lopachev, Alexander, et al.
Publicado: (2019)

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Na(+),K(+)-ATPase and Cardiotonic Steroids in Models of Dopaminergic System Pathologies
por: Markina, Alisa A., et al.
Publicado: (2023)

ARGEOS: A New Bioinformatic Tool for Detailed Systematics Search in GEO and ArrayExpress
por: Gavrish, Gleb E., et al.
Publicado: (2021)

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na(+),K(+)-ATPase-mediated signaling
por: Smolyaninova, Larisa V., et al.
Publicado: (2019)

Brain-related genes are specifically enriched with long phase 1 introns
por: Baulin, Eugene F., et al.
Publicado: (2020)

Neurotoxic potential of reactive astrocytes in canine distemper demyelinating leukoencephalitis
por: Klemens, J., et al.
Publicado: (2019)

Editorial: Oxylipins: The Front Line of Plant Interactions
por: Sugimoto, Koichi, et al.
Publicado: (2022)

A low-cost and customizable alternative for commercial implantable cannula for intracerebral administration in mice
por: Kazanskaya, Rogneda B., et al.
Publicado: (2020)

Neuroprotective Efficacy of a Nanomicellar Complex of Carnosine and Lipoic Acid in a Rat Model of Rotenone-Induced Parkinson’s Disease
por: Kulikova, Olga, et al.
Publicado: (2023)

Necroptosis in CNS diseases: Focus on astrocytes
por: Mitroshina, Elena V., et al.
Publicado: (2023)

The clinical translation of eicosanoids and other oxylipins, although challenging, should be actively pursued
por: Gladine, Cécile, et al.
Publicado: (2021)

Hemodialysis and Plasma Oxylipin Biotransformation in Peripheral Tissue
por: Liu, Tong, et al.
Publicado: (2022)

Allene Oxide Synthase Pathway in Cereal Roots: Detection of Novel Oxylipin Graminoxins
por: Grechkin, Alexander N., et al.
Publicado: (2018)

Acyl-Lipid Δ(6)-Desaturase May Act as a First FAD in Cyanobacteria
por: Starikov, Alexander Y., et al.
Publicado: (2022)

Collection and Storage of Human Plasma for Measurement of Oxylipins
por: Polinski, Kristen J., et al.
Publicado: (2021)

Transcriptome and Oxylipin Profiling Joint Analysis Reveals Opposite Roles of 9-Oxylipins and Jasmonic Acid in Maize Resistance to Gibberella Stalk Rot
por: Wang, Qing, et al.
Publicado: (2021)

Astrocyte Dysfunctions and HIV-1 Neurotoxicity
por: Ton, Hoai, et al.
Publicado: (2013)

Role of astrocytes in manganese mediated neurotoxicity
por: Sidoryk-Wegrzynowicz, Marta, et al.
Publicado: (2013)

Ketols Emerge as Potent Oxylipin Signals Regulating Diverse Physiological Processes in Plants
por: Berg-Falloure, Katherine M., et al.
Publicado: (2023)

Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population
por: Buckner, Teresa, et al.
Publicado: (2023)

Oxylipins in moss development and defense
por: de León, Inés Ponce, et al.
Publicado: (2015)

Effects of hemodialysis on plasma oxylipins
por: Gollasch, Benjamin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pg5v84u1uvdl5j1t75c07lct0k