Cargando…
Recent Advances in BTK Inhibitors for the Treatment of Inflammatory and Autoimmune Diseases
Bruton’s tyrosine kinase (BTK) plays a crucial role in B-cell receptor and Fc receptor signaling pathways. BTK is also involved in the regulation of Toll-like receptors and chemokine receptors. Given the central role of BTK in immunity, BTK inhibition represents a promising therapeutic approach for...
Autores principales: | Zhang, Datong, Gong, He, Meng, Fancui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399599/ https://www.ncbi.nlm.nih.gov/pubmed/34443496 http://dx.doi.org/10.3390/molecules26164907 |
Ejemplares similares
-
Bruton’s Tyrosine Kinase (BTK) Inhibitors and Autoimmune Diseases: Making Sense of BTK Inhibitor Specificity Profiles and Recent Clinical Trial Successes and Failures
por: Ringheim, Garth E., et al.
Publicado: (2021) -
BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies
por: Alu, Aqu, et al.
Publicado: (2022) -
Managing chronic lymphocytic leukemia in 2020: an update on recent clinical advances with a focus on BTK and BCL-2 inhibitors
por: Bose, Prithviraj, et al.
Publicado: (2021) -
Managing Waldenström’s macroglobulinemia with BTK inhibitors
por: Buske, Christian, et al.
Publicado: (2022) -
Acquired BTK mutations associated with resistance to noncovalent BTK inhibitors
por: Qi, Jialei, et al.
Publicado: (2023)