Cargando…

Polymeric Lipid Hybrid Nanoparticles (PLNs) as Emerging Drug Delivery Platform—A Comprehensive Review of Their Properties, Preparation Methods, and Therapeutic Applications

Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a polymeric kernel and lipid/lipid–PEG shells that have the physical stability and biocompatibility of both polymeric nanoparticles and liposomes. PLNs have emerged as a highly potent and promising nanocarrier for a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sivadasan, Durgaramani, Sultan, Muhammad Hadi, Madkhali, Osama, Almoshari, Yosif, Thangavel, Neelaveni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399620/ https://www.ncbi.nlm.nih.gov/pubmed/34452251 http://dx.doi.org/10.3390/pharmaceutics13081291

Ejemplares similares

Development and Optimization of Methylcellulose-Based Nanoemulgel Loaded with Nigella sativa Oil for Oral Health Management: Quadratic Model Approach
por: Sultan, Muhammad H., et al.
Publicado: (2022)

Cubosomes in Drug Delivery—A Comprehensive Review on Its Structural Components, Preparation Techniques and Therapeutic Applications
por: Sivadasan, Durgaramani, et al.
Publicado: (2023)

A Review of the Structure, Preparation, and Application of NLCs, PNPs, and PLNs
por: Li, Qianwen, et al.
Publicado: (2017)

Osmotic Pump Drug Delivery Systems—A Comprehensive Review
por: Almoshari, Yosif
Publicado: (2022)

Stealth Liposomes (PEGylated) Containing an Anticancer Drug Camptothecin: In Vitro Characterization and In Vivo Pharmacokinetic and Tissue Distribution Study
por: Sivadasan, Durgaramani, et al.
Publicado: (2022)

Novel Hydrogels for Topical Applications: An Updated Comprehensive Review Based on Source
por: Almoshari, Yosif
Publicado: (2022)

Design and characterization of Lactotransferrin peptide-loaded dextran-docosahexaenoic acid nanoparticles: an immune modulator for hepatic damage
por: Madkhali, Osama A., et al.
Publicado: (2023)

Induction of Innate and Adaptive Immune Response against Recombinant HBsAg Protein Entrapped in Docosahexaenoic Acid Nanovesicles through Biomarkers
por: Bakkari, Mohammed Ali, et al.
Publicado: (2023)

Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals
por: Sultan, Muhammad H., et al.
Publicado: (2023)

Development, Therapeutic Evaluation and Theranostic Applications of Cubosomes on Cancers: An Updated Review
por: Almoshari, Yosif
Publicado: (2022)

Medicinal plants used for dermatological disorders among the people of the kingdom of Saudi Arabia: A narrative review
por: Almoshari, Yosif
Publicado: (2022)

Strategies to Improvise Organ Donor Pool: A Study on the Knowledge, Attitudes, and Performance of Higher Secondary School Teachers Towards the Organ Donation
por: Venkatesan, Krishnaraju, et al.
Publicado: (2022)

Solid Lipid Nanoparticles: Applications and Prospects in Cancer Treatment
por: Sivadasan, Durgaramani, et al.
Publicado: (2023)

Pancreatic draining lymph nodes (PLNs) serve as a pathogenic hub contributing to the development of type 1 diabetes
por: Sun, Fei, et al.
Publicado: (2023)

Fabrication of Capsaicin Loaded Nanocrystals: Physical Characterizations and In Vivo Evaluation
por: Khan, Barkat Ali, et al.
Publicado: (2021)

Perspectives and Prospective on Solid Lipid Nanoparticles as Drug Delivery Systems
por: Madkhali, Osama A.
Publicado: (2022)

Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John’s Wort Plant Constituents and Their Potential for the Treatment of Depression
por: Salawi, Ahmad, et al.
Publicado: (2023)

Characterization of cisplatin-loaded chitosan nanoparticles and rituximab-linked surfaces as target-specific injectable nano-formulations for combating cancer
por: Sultan, Muhammad H., et al.
Publicado: (2022)

Application of Box–Behnken Design in the Optimization and Preparation of Salicylic Acid Nanopowder using Solvent-Free Green Mechanochemical Approach
por: Javed, Shamama, et al.
Publicado: (2023)

How many ELNs are optimal for breast cancer patients with more than three PLNs who underwent MRM? A large population-based study
por: Wang, Xiaohui, et al.
Publicado: (2018)

Development of nanocubosomes co-loaded with dual anticancer agents curcumin and temozolomide for effective Colon cancer therapy
por: Almoshari, Yosif, et al.
Publicado: (2022)

Pharmacophore model-aided virtual screening combined with comparative molecular docking and molecular dynamics for identification of marine natural products as SARS-CoV-2 papain-like protease inhibitors
por: Thangavel, Neelaveni, et al.
Publicado: (2022)

Benchmarked molecular docking integrated molecular dynamics stability analysis for prediction of SARS-CoV-2 papain-like protease inhibition by olive secoiridoids
por: Thangavel, Neelaveni, et al.
Publicado: (2023)

A comprehensive review on potential applications of metallic nanoparticles as antifungal therapies to combat human fungal diseases
por: Madkhali, Osama A.
Publicado: (2023)

Technologies for Solubility, Dissolution and Permeation Enhancement of Natural Compounds
por: Alshamrani, Meshal, et al.
Publicado: (2022)

Ribociclib Hybrid Lipid–Polymer Nanoparticle Preparation and Characterization for Cancer Treatment
por: Al-Shdefat, Ramadan, et al.
Publicado: (2023)

Orally Administered, Biodegradable and Biocompatible Hydroxypropyl–β–Cyclodextrin Grafted Poly(methacrylic acid) Hydrogel for pH Sensitive Sustained Anticancer Drug Delivery
por: Batool, Nighat, et al.
Publicado: (2022)

A review of nanomaterials from synthetic and natural molecules for prospective breast cancer nanotherapy
por: Kumar, Pankaj, et al.
Publicado: (2023)

One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants
por: Rokkarukala, Samson, et al.
Publicado: (2023)

Press-Coated Aceclofenac Tablets for Pulsatile Drug Delivery: Formulation and In Vitro Evaluations
por: Rashid, Rizwana, et al.
Publicado: (2022)

Drug Encapsulated Lipid-Polymeric Nanohybrid as a Chemo-therapeutic Platform of Cancer
por: Kumar, Rahul, et al.
Publicado: (2023)

Polymeric Hydrogels as Technology Platform for Drug Delivery Applications
por: Sosnik, Alejandro, et al.
Publicado: (2017)

An Innovative Polymeric Platform for Controlled and Localized Drug Delivery
por: Elbjorn, Monica, et al.
Publicado: (2023)

Drug Delivery of Gelatin Nanoparticles as a Biodegradable Polymer for the Treatment of Infectious Diseases: Perspectives and Challenges
por: Madkhali, Osama A.
Publicado: (2023)

Design of Hybrid Polymeric-Lipid Nanoparticles Using Curcumin as a Model: Preparation, Characterization, and In Vitro Evaluation of Demethoxycurcumin and Bisdemethoxycurcumin-Loaded Nanoparticles
por: Wilhelm Romero, Krissia, et al.
Publicado: (2021)

Development of Statistically Optimized Chemically Cross-Linked Hydrogel for the Sustained-Release Delivery of Favipiravir
por: Salawi, Ahmad, et al.
Publicado: (2022)

A cooperative polymeric platform for tumor-targeted drug delivery
por: Song, Wantong, et al.
Publicado: (2016)

Polymerized porin as a novel delivery platform for coronavirus vaccine
por: Yang, Zhongqian, et al.
Publicado: (2022)

Preparation and Deep Characterization of Composite/Hybrid Multi-Scale and Multi-Domain Polymeric Microparticles
por: Yu, Wei, et al.
Publicado: (2019)

Hepatoprotective Effect of Curcumin Nano-Lipid Carrier against Cypermethrin Toxicity by Countering the Oxidative, Inflammatory, and Apoptotic Changes in Wistar Rats
por: Hussain, Sohail, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_70bbvqngg5s5ef6v30r7pu2a67