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Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia

Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1...

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Autores principales: Skopljanac, Ivan, Ivelja, Mirela Pavicic, Barcot, Ognjen, Brdar, Ivan, Dolic, Kresimir, Polasek, Ozren, Radic, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399683/
https://www.ncbi.nlm.nih.gov/pubmed/34442401
http://dx.doi.org/10.3390/jpm11080757
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author Skopljanac, Ivan
Ivelja, Mirela Pavicic
Barcot, Ognjen
Brdar, Ivan
Dolic, Kresimir
Polasek, Ozren
Radic, Mislav
author_facet Skopljanac, Ivan
Ivelja, Mirela Pavicic
Barcot, Ognjen
Brdar, Ivan
Dolic, Kresimir
Polasek, Ozren
Radic, Mislav
author_sort Skopljanac, Ivan
collection PubMed
description Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1 November 2020, to 22 March 2021. The LUS protocol was based on the assessment of 14 lung zones with a total score up to 42, which was compared to the disease severity and fatality. Results: A total of 133 patients with COVID-19 pneumonia confirmed by RT-PCR were enrolled, with a median time from hospital admission to lung ultrasound of one day. The LUS score was correlated with clinical severity at hospital admission (Spearman’s rho 0.40, 95% CI 0.24 to 0.53, p < 0.001). Patients with higher LUS scores were experiencing greater disease severity; a high flow nasal cannula had an odds ratio of 1.43 (5% CI 1.17–1.74) in patients with LUS score > 29; the same score also predicted the need for mechanical ventilation (1.25, [1.07–1.48]). An LUS score > 30 (1.41 [1.18–1.68]) and age over 68 (1.26 [1.11–1.43]) were significant predictors of fatality. Conclusions: LUS at hospital admission is shown to have a high predictive power of the severity and fatality of COVID-19 pneumonia.
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spelling pubmed-83996832021-08-29 Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia Skopljanac, Ivan Ivelja, Mirela Pavicic Barcot, Ognjen Brdar, Ivan Dolic, Kresimir Polasek, Ozren Radic, Mislav J Pers Med Article Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1 November 2020, to 22 March 2021. The LUS protocol was based on the assessment of 14 lung zones with a total score up to 42, which was compared to the disease severity and fatality. Results: A total of 133 patients with COVID-19 pneumonia confirmed by RT-PCR were enrolled, with a median time from hospital admission to lung ultrasound of one day. The LUS score was correlated with clinical severity at hospital admission (Spearman’s rho 0.40, 95% CI 0.24 to 0.53, p < 0.001). Patients with higher LUS scores were experiencing greater disease severity; a high flow nasal cannula had an odds ratio of 1.43 (5% CI 1.17–1.74) in patients with LUS score > 29; the same score also predicted the need for mechanical ventilation (1.25, [1.07–1.48]). An LUS score > 30 (1.41 [1.18–1.68]) and age over 68 (1.26 [1.11–1.43]) were significant predictors of fatality. Conclusions: LUS at hospital admission is shown to have a high predictive power of the severity and fatality of COVID-19 pneumonia. MDPI 2021-07-30 /pmc/articles/PMC8399683/ /pubmed/34442401 http://dx.doi.org/10.3390/jpm11080757 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Skopljanac, Ivan
Ivelja, Mirela Pavicic
Barcot, Ognjen
Brdar, Ivan
Dolic, Kresimir
Polasek, Ozren
Radic, Mislav
Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title_full Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title_fullStr Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title_full_unstemmed Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title_short Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
title_sort role of lung ultrasound in predicting clinical severity and fatality in covid-19 pneumonia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399683/
https://www.ncbi.nlm.nih.gov/pubmed/34442401
http://dx.doi.org/10.3390/jpm11080757
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