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Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia
Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399683/ https://www.ncbi.nlm.nih.gov/pubmed/34442401 http://dx.doi.org/10.3390/jpm11080757 |
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author | Skopljanac, Ivan Ivelja, Mirela Pavicic Barcot, Ognjen Brdar, Ivan Dolic, Kresimir Polasek, Ozren Radic, Mislav |
author_facet | Skopljanac, Ivan Ivelja, Mirela Pavicic Barcot, Ognjen Brdar, Ivan Dolic, Kresimir Polasek, Ozren Radic, Mislav |
author_sort | Skopljanac, Ivan |
collection | PubMed |
description | Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1 November 2020, to 22 March 2021. The LUS protocol was based on the assessment of 14 lung zones with a total score up to 42, which was compared to the disease severity and fatality. Results: A total of 133 patients with COVID-19 pneumonia confirmed by RT-PCR were enrolled, with a median time from hospital admission to lung ultrasound of one day. The LUS score was correlated with clinical severity at hospital admission (Spearman’s rho 0.40, 95% CI 0.24 to 0.53, p < 0.001). Patients with higher LUS scores were experiencing greater disease severity; a high flow nasal cannula had an odds ratio of 1.43 (5% CI 1.17–1.74) in patients with LUS score > 29; the same score also predicted the need for mechanical ventilation (1.25, [1.07–1.48]). An LUS score > 30 (1.41 [1.18–1.68]) and age over 68 (1.26 [1.11–1.43]) were significant predictors of fatality. Conclusions: LUS at hospital admission is shown to have a high predictive power of the severity and fatality of COVID-19 pneumonia. |
format | Online Article Text |
id | pubmed-8399683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83996832021-08-29 Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia Skopljanac, Ivan Ivelja, Mirela Pavicic Barcot, Ognjen Brdar, Ivan Dolic, Kresimir Polasek, Ozren Radic, Mislav J Pers Med Article Background: Lung ultrasound (LUS) is a useful imaging method for identifying COVID-19 pneumonia. The aim of this study was to explore the role of LUS in predicting the severity of the disease and fatality in patients with COVID-19. Methods: This was a single-center, follow-up study, conducted from 1 November 2020, to 22 March 2021. The LUS protocol was based on the assessment of 14 lung zones with a total score up to 42, which was compared to the disease severity and fatality. Results: A total of 133 patients with COVID-19 pneumonia confirmed by RT-PCR were enrolled, with a median time from hospital admission to lung ultrasound of one day. The LUS score was correlated with clinical severity at hospital admission (Spearman’s rho 0.40, 95% CI 0.24 to 0.53, p < 0.001). Patients with higher LUS scores were experiencing greater disease severity; a high flow nasal cannula had an odds ratio of 1.43 (5% CI 1.17–1.74) in patients with LUS score > 29; the same score also predicted the need for mechanical ventilation (1.25, [1.07–1.48]). An LUS score > 30 (1.41 [1.18–1.68]) and age over 68 (1.26 [1.11–1.43]) were significant predictors of fatality. Conclusions: LUS at hospital admission is shown to have a high predictive power of the severity and fatality of COVID-19 pneumonia. MDPI 2021-07-30 /pmc/articles/PMC8399683/ /pubmed/34442401 http://dx.doi.org/10.3390/jpm11080757 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Skopljanac, Ivan Ivelja, Mirela Pavicic Barcot, Ognjen Brdar, Ivan Dolic, Kresimir Polasek, Ozren Radic, Mislav Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title | Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title_full | Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title_fullStr | Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title_full_unstemmed | Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title_short | Role of Lung Ultrasound in Predicting Clinical Severity and Fatality in COVID-19 Pneumonia |
title_sort | role of lung ultrasound in predicting clinical severity and fatality in covid-19 pneumonia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399683/ https://www.ncbi.nlm.nih.gov/pubmed/34442401 http://dx.doi.org/10.3390/jpm11080757 |
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