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Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices

The search for coatings that extend the useful life of biomedical devices has been of great interest, and titanium has been of great relevance due to its innocuousness and low reactivity. This study contributes to the investigation of Ti/Ag films in different configurations (monolayer and multilayer...

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Autores principales: Mina-Aponzá, Sebastián, Castro-Narváez, Sandra Patricia, Caicedo-Bejarano, Luz Dary, Bermeo-Acosta, Franklin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399690/
https://www.ncbi.nlm.nih.gov/pubmed/34443400
http://dx.doi.org/10.3390/molecules26164813
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author Mina-Aponzá, Sebastián
Castro-Narváez, Sandra Patricia
Caicedo-Bejarano, Luz Dary
Bermeo-Acosta, Franklin
author_facet Mina-Aponzá, Sebastián
Castro-Narváez, Sandra Patricia
Caicedo-Bejarano, Luz Dary
Bermeo-Acosta, Franklin
author_sort Mina-Aponzá, Sebastián
collection PubMed
description The search for coatings that extend the useful life of biomedical devices has been of great interest, and titanium has been of great relevance due to its innocuousness and low reactivity. This study contributes to the investigation of Ti/Ag films in different configurations (monolayer and multilayer) deposited by magnetron sputtering. The sessile droplet technique was applied to study wettability; greater film penetrability was obtained when Ag is the external layer, conferring high efficiency in cell adhesion. The morphological properties were characterized by SEM, which showed porous nuclei on the surface in the Ag coating and crystals embedded in the Ti film. The structural properties were studied by XRD, revealing the presence of TiO(2) in the anatase crystalline phase in a proportion of 49.9% and the formation of a silver cubic network centered on the faces. Tafel polarization curves demonstrated improvements in the corrosion current densities of Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti and Ti/Ag compared to the Ag coating, with values of 0.1749, 0.4802, and 2.044 nA.m(−2), respectively. Antimicrobial activity was evaluated against the bacteria Pseudomonas aeruginosa and Bacillus subtilis and the yeasts Candida krusei and Candida albicans, revealing that the Ti/Ag and Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti coatings exhibit promise in biomedical material applications.
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spelling pubmed-83996902021-08-29 Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices Mina-Aponzá, Sebastián Castro-Narváez, Sandra Patricia Caicedo-Bejarano, Luz Dary Bermeo-Acosta, Franklin Molecules Article The search for coatings that extend the useful life of biomedical devices has been of great interest, and titanium has been of great relevance due to its innocuousness and low reactivity. This study contributes to the investigation of Ti/Ag films in different configurations (monolayer and multilayer) deposited by magnetron sputtering. The sessile droplet technique was applied to study wettability; greater film penetrability was obtained when Ag is the external layer, conferring high efficiency in cell adhesion. The morphological properties were characterized by SEM, which showed porous nuclei on the surface in the Ag coating and crystals embedded in the Ti film. The structural properties were studied by XRD, revealing the presence of TiO(2) in the anatase crystalline phase in a proportion of 49.9% and the formation of a silver cubic network centered on the faces. Tafel polarization curves demonstrated improvements in the corrosion current densities of Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti and Ti/Ag compared to the Ag coating, with values of 0.1749, 0.4802, and 2.044 nA.m(−2), respectively. Antimicrobial activity was evaluated against the bacteria Pseudomonas aeruginosa and Bacillus subtilis and the yeasts Candida krusei and Candida albicans, revealing that the Ti/Ag and Ag/Ti/Ag/Ti/Ag/Ti/Ag/Ti coatings exhibit promise in biomedical material applications. MDPI 2021-08-09 /pmc/articles/PMC8399690/ /pubmed/34443400 http://dx.doi.org/10.3390/molecules26164813 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mina-Aponzá, Sebastián
Castro-Narváez, Sandra Patricia
Caicedo-Bejarano, Luz Dary
Bermeo-Acosta, Franklin
Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title_full Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title_fullStr Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title_full_unstemmed Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title_short Study of Titanium–Silver Monolayer and Multilayer Films for Protective Applications in Biomedical Devices
title_sort study of titanium–silver monolayer and multilayer films for protective applications in biomedical devices
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399690/
https://www.ncbi.nlm.nih.gov/pubmed/34443400
http://dx.doi.org/10.3390/molecules26164813
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