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Seeing the forest through the trees: prioritising potentially functional interactions from Hi-C

Eukaryotic genomes are highly organised within the nucleus of a cell, allowing widely dispersed regulatory elements such as enhancers to interact with gene promoters through physical contacts in three-dimensional space. Recent chromosome conformation capture methodologies such as Hi-C have enabled t...

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Detalles Bibliográficos
Autores principales:	Liu, Ning, Low, Wai Yee, Alinejad-Rokny, Hamid, Pederson, Stephen, Sadlon, Timothy, Barry, Simon, Breen, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399707/ https://www.ncbi.nlm.nih.gov/pubmed/34454581 http://dx.doi.org/10.1186/s13072-021-00417-4

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