GMP-Compliant Radiosynthesis of [(18)F]GP1, a Novel PET Tracer for the Detection of Thrombi

Thrombus formation and thromboembolic events play important roles in various cardiovascular pathologies. The key receptor involved in platelet aggregation is the fibrinogen receptor glycoprotein IIb/IIIa. [(18)F]GP1, a derivative of the GPIIb/IIIa antagonist elarofiban, is a specific (18)F-labeled s...

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Detalles Bibliográficos
Autores principales: Hugenberg, Verena, Zerna, Marion, Berndt, Mathias, Zabel, Reinhard, Preuss, Rainer, Rolfsmeier, Dirk, Wegener, Janet, Fox, Henrik, Kassner, Astrid, Milting, Hendrik, Koglin, Norman, Stephens, Andrew W., Gummert, Jan F., Burchert, Wolfgang, Deutsch, Marcus-André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399972/
https://www.ncbi.nlm.nih.gov/pubmed/34451836
http://dx.doi.org/10.3390/ph14080739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399972/
https://www.ncbi.nlm.nih.gov/pubmed/34451836
http://dx.doi.org/10.3390/ph14080739

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