Cargando…

GMP-Compliant Radiosynthesis of [(18)F]GP1, a Novel PET Tracer for the Detection of Thrombi

Thrombus formation and thromboembolic events play important roles in various cardiovascular pathologies. The key receptor involved in platelet aggregation is the fibrinogen receptor glycoprotein IIb/IIIa. [(18)F]GP1, a derivative of the GPIIb/IIIa antagonist elarofiban, is a specific (18)F-labeled s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hugenberg, Verena, Zerna, Marion, Berndt, Mathias, Zabel, Reinhard, Preuss, Rainer, Rolfsmeier, Dirk, Wegener, Janet, Fox, Henrik, Kassner, Astrid, Milting, Hendrik, Koglin, Norman, Stephens, Andrew W., Gummert, Jan F., Burchert, Wolfgang, Deutsch, Marcus-André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399972/ https://www.ncbi.nlm.nih.gov/pubmed/34451836 http://dx.doi.org/10.3390/ph14080739

Ejemplares similares

Commentary to (18)F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi: Imaging Activated Platelets in Clots—Are We Getting There?
por: Stephens, Andrew W., et al.
Publicado: (2018)

GMP-compliant fully automated radiosynthesis of [(18)F]FEPPA for PET/MRI imaging of regional brain TSPO expression
por: Chang, Chi-Wei, et al.
Publicado: (2021)

GMP Compliant Synthesis of [(18)F]Canagliflozin, a Novel PET Tracer for the Sodium–Glucose Cotransporter 2
por: van der Hoek, Sjoukje, et al.
Publicado: (2021)

Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [(68)Ga]Ga-ABY-025 tracer
por: Jussing, Emma, et al.
Publicado: (2023)

Determination of radionuclides and radiochemical impurities produced by in-house cyclotron irradiation and subsequent radiosynthesis of PET tracers
por: Ishiwata, Kiichi, et al.
Publicado: (2016)

Radiosynthesis and Biological Evaluation of N-[(18)F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer
por: Hu, Kongzhen, et al.
Publicado: (2014)

Radiosynthesis and Preliminary Biological Evaluation of (18)F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging
por: Zhao, Jing, et al.
Publicado: (2018)

Radiosynthesis of the norepinephrine transporter tracer [(18)F]NS12137 via copper‐mediated (18) F‐labelling
por: Lahdenpohja, Salla, et al.
Publicado: (2019)

Procedures for the GMP-Compliant Production and Quality Control of [(18)F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer
por: Cardinale, Jens, et al.
Publicado: (2017)

Radiosynthesis of [(11)C]SNAP-7941—the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1)
por: Philippe, C., et al.
Publicado: (2012)

Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [(123)I]-CLINME, a New SPECT Tracer for the Translocator Protein
por: Mattner, F., et al.
Publicado: (2015)

Radiosynthesis and preliminary biological evaluation of N-(2-[(18)F]fluoropropionyl)-L-glutamine as a PET tracer for tumor imaging
por: Tang, Caihua, et al.
Publicado: (2016)

New protein deposition tracers in the pipeline
por: Jovalekic, Aleksandar, et al.
Publicado: (2016)

Standardized GMP-compliant scalable production of human pancreas organoids
por: Dossena, Marta, et al.
Publicado: (2020)

High-yielding (18)F radiosynthesis of a novel oxytocin receptor tracer, a probe for nose-to-brain oxytocin uptake in vivo
por: Beard, Rhiannon, et al.
Publicado: (2018)

Fully-automated radiosynthesis of the amyloid tracer [(11)C] PiB via direct [(11)C]CO(2) fixation-reduction
por: Buccino, Pablo, et al.
Publicado: (2019)

Radiosynthesis and in vivo evaluation of (11)C-labeled BMS-193885 and its desmethyl analog as PET tracers for neuropeptide Y1 receptors
por: Kawamura, Kazunori, et al.
Publicado: (2019)

Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid
por: Hugenberg, Verena, et al.
Publicado: (2018)

Cell-based medicinal products and the development of GMP-compliant processes and manufacturing
por: Romagnoli, Luca, et al.
Publicado: (2011)

GMP-Compliant Isolation and Large-Scale Expansion of Bone Marrow-Derived MSC
por: Fekete, Natalie, et al.
Publicado: (2012)

Automated GMP compliant production of [(18)F]AlF-NOTA-octreotide
por: Tshibangu, Térence, et al.
Publicado: (2020)

Creation of GMP-Compliant iPSCs From Banked Umbilical Cord Blood
por: Tian, Pei, et al.
Publicado: (2022)

Development and Validation of a GMP-Compliant High-Pressure Liquid Chromatography Method for the Determination of the Chemical and Radiochemical Purity of [(18)F]PSMA-1007, a PET Tracer for the Imaging of Prostate Cancer
por: Katzschmann, Ines, et al.
Publicado: (2021)

Human Induced Pluripotent Stem-Cell-Derived Cardiomyocytes as Models for Genetic Cardiomyopathies
por: Brodehl, Andreas, et al.
Publicado: (2019)

Fully Automated GMP-Compliant Synthesis of [(18)F]FE-PE2I
por: Bratteby, Klas, et al.
Publicado: (2021)

Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets
por: Fonseca, Alexandra I., et al.
Publicado: (2022)

Radiosynthesis of [(18)F]Trifluoroalkyl Groups: Scope and Limitations
por: Lien, V. T., et al.
Publicado: (2014)

Improved Automated Radiosynthesis of [(11)C]PBR28
por: Solingapuram Sai, Kiran Kumar, et al.
Publicado: (2015)

Radiosynthesis and reactivity of N-[(11)C]methyl carbamoylimidazole
por: Kadirvel, Manikandan, et al.
Publicado: (2018)

Fibrinolysis in Platelet Thrombi
por: Kanji, Rahim, et al.
Publicado: (2021)

Radiosynthesis and validation of (±)-[(18)F]-3-fluoro-2-hydroxypropionate ([(18)F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors
por: Van Hée, Vincent F., et al.
Publicado: (2017)

One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[(123,125)I]iodo-1,2,3-triazole derived Isatin SPECT Tracer
por: Glaser, Matthias, et al.
Publicado: (2019)

Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation
por: Radisch, Sabine, et al.
Publicado: (2022)

Optimised GMP-compliant production of [(18)F]DPA-714 on the Trasis AllinOne module
por: Cybulska, Klaudia A., et al.
Publicado: (2021)

The N-Terminal Part of the 1A Domain of Desmin Is a Hot Spot Region for Putative Pathogenic DES Mutations Affecting Filament Assembly
por: Brodehl, Andreas, et al.
Publicado: (2022)

Pre‐operative risk factors for driveline infection in left ventricular‐assist device patients
por: Köhler, Ann‐Kristin, et al.
Publicado: (2022)

Large thrombus in transit in a COVID-19 patient
por: Bleiziffer, Sabine, et al.
Publicado: (2022)

A New Method for Radiosynthesis of (11)C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [(11)C]GR103545
por: Schoultz, B.W, et al.
Publicado: (2008)

Automated One-pot Radiosynthesis of [(11)C]S-adenosyl Methionine
por: Zoppolo, Florencia, et al.
Publicado: (2017)

Pitfalls and solutions of the fully-automated radiosynthesis of [(11)C]metoclopramide
por: Pichler, Verena, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n66u6l7o5iniotjslvkllbel23