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Flavylium-Based Hypoxia-Responsive Probe for Cancer Cell Imaging

A hypoxia-responsive probe based on a flavylium dye containing an azo group (AZO-Flav) was synthesized to detect hypoxic conditions via a reductase-catalyzed reaction in cancer cells. In in vitro enzymatic investigation, the azo group of AZO-Flav was reduced by a reductase in the presence of reduced...

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Detalles Bibliográficos
Autores principales: Pewklang, Thitima, Wet-osot, Sirawit, Wangngae, Sirilak, Ngivprom, Utumporn, Chansaenpak, Kantapat, Duangkamol, Chuthamat, Lai, Rung-Yi, Noisa, Parinya, Sukwattanasinitt, Mongkol, Kamkaew, Anyanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400153/
https://www.ncbi.nlm.nih.gov/pubmed/34443527
http://dx.doi.org/10.3390/molecules26164938