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TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell

Transcription factor 19 (TCF19) is a gene associated with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in genome-wide association studies. Prior studies have demonstrated that Tcf19 knockdown impairs β-cell proliferation and increases apoptosis. However, little is known about its role in diabet...

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Detalles Bibliográficos
Autores principales: Yang, Grace H., Fontaine, Danielle A., Lodh, Sukanya, Blumer, Joseph T., Roopra, Avtar, Davis, Dawn Belt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400192/
https://www.ncbi.nlm.nih.gov/pubmed/34436454
http://dx.doi.org/10.3390/metabo11080513