Lyoprotective Effects of Mannitol and Lactose Compared to Sucrose and Trehalose: Sildenafil Citrate Liposomes as a Case Study

The lyoprotective effects of mannitol and lactose have been evaluated in the production of sildenafil citrate liposomes. Liposomes were prepared by mixing the components under ultrasonic agitation, followed by a transmembrane pH gradient for remote drug loading. Mannitol and lactose, as compared to...

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Detalles Bibliográficos
Autores principales: de Jesús Valle, María José, Alves, Andreía, Coutinho, Paula, Prata Ribeiro, Maximiano, Maderuelo, Cristina, Sánchez Navarro, Amparo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400243/
https://www.ncbi.nlm.nih.gov/pubmed/34452127
http://dx.doi.org/10.3390/pharmaceutics13081164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400243/
https://www.ncbi.nlm.nih.gov/pubmed/34452127
http://dx.doi.org/10.3390/pharmaceutics13081164

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