2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum

The malaria parasite harbors a relict plastid called the apicoplast. Although not photosynthetic, the apicoplast retains unusual, non-mammalian metabolic pathways that are essential to the parasite, opening up a new perspective for the development of novel antimalarials which display a new mechanism...

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Detalles Bibliográficos
Autores principales: Amrane, Dyhia, Arnold, Christophe-Sébastien, Hutter, Sébastien, Sanz-Serrano, Julen, Collia, Miguel, Azqueta, Amaya, Paloque, Lucie, Cohen, Anita, Amanzougaghene, Nadia, Tajeri, Shahin, Franetich, Jean-François, Mazier, Dominique, Benoit-Vical, Françoise, Verhaeghe, Pierre, Azas, Nadine, Vanelle, Patrice, Botté, Cyrille, Primas, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400257/
https://www.ncbi.nlm.nih.gov/pubmed/34451821
http://dx.doi.org/10.3390/ph14080724

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