Novel Anti-Melanogenic Compounds, (Z)-5-(Substituted Benzylidene)-4-thioxothiazolidin-2-one Derivatives: In Vitro and In Silico Insights

To confirm that the β-phenyl-α,β-unsaturated thiocarbonyl (PUSTC) scaffold, similar to the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, acts as a core inhibitory structure for tyrosinase, twelve (Z)-5-(substituted benzylidene)-4-thioxothiazolidin-2-one ((Z)-BTTZ) derivatives were designed and...

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Detalles Bibliográficos
Autores principales: Choi, Heejeong, Ryu, Il Young, Choi, Inkyu, Ullah, Sultan, Jung, Hee Jin, Park, Yujin, Jeong, Yeongmu, Hwang, YeJi, Hong, Sojeong, Yoon, In-Soo, Yun, Hwayoung, Kim, Min-Soo, Yoo, Jin-Wook, Jung, Yunjin, Chun, Pusoon, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400311/
https://www.ncbi.nlm.nih.gov/pubmed/34443550
http://dx.doi.org/10.3390/molecules26164963

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