Cargando…

Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention

The phosphatidylinositol 3-kinase (PI3K)/serine-threonine kinase (Akt)/mammalian target of the rapamycin (mTOR)-signaling pathway has been suggested to have connections with the malignant transformation, growth, proliferation, and metastasis of various cancers and solid tumors. Relevant connections...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roudsari, Nazanin Momeni, Lashgari, Naser-Aldin, Momtaz, Saeideh, Abaft, Shaghayegh, Jamali, Fatemeh, Safaiepour, Pardis, Narimisa, Kiyana, Jackson, Gloria, Bishayee, Anusha, Rezaei, Nima, Abdolghaffari, Amir Hossein, Bishayee, Anupam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400324/ https://www.ncbi.nlm.nih.gov/pubmed/34452154 http://dx.doi.org/10.3390/pharmaceutics13081195

Ejemplares similares

Transmembrane serine protease 2 and angiotensin-converting enzyme 2 anti-inflammatory receptors for COVID-19/inflammatory bowel diseases treatment
por: Lashgari, Naser-Aldin, et al.
Publicado: (2021)

Statins block mammalian target of rapamycin pathway: a possible novel therapeutic strategy for inflammatory, malignant and neurodegenerative diseases
por: Lashgari, Naser-Aldin, et al.
Publicado: (2022)

Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis
por: Bishayee, Anupam, et al.
Publicado: (2016)

Targeting transforming growth factor‐β signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin
por: Tewari, Devesh, et al.
Publicado: (2022)

Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways
por: Kamalian, Aida, et al.
Publicado: (2020)

The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review
por: Das, Niranjan, et al.
Publicado: (2021)

Oleuropein and Cancer Chemoprevention: The Link is Hot
por: Ahmad Farooqi, Ammad, et al.
Publicado: (2017)

Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy
por: Ghanbari-Movahed, Maryam, et al.
Publicado: (2021)

Pharmacological effects of gallic acid in health and diseases: A mechanistic review
por: Kahkeshani, Niloofar, et al.
Publicado: (2019)

Molecular Mechanisms Underlying Cancer Prevention and Intervention with Bioactive Food Components
por: Bishayee, Anupam
Publicado: (2023)

d-Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis
por: Rabi, Thangaiyan, et al.
Publicado: (2009)

Trianthema portulacastrum Linn. Displays Anti-Inflammatory Responses during Chemically Induced Rat Mammary Tumorigenesis through Simultaneous and Differential Regulation of NF-κB and Nrf2 Signaling Pathways
por: Mandal, Animesh, et al.
Publicado: (2015)

Mechanism of Breast Cancer Preventive Action of Pomegranate: Disruption of Estrogen Receptor and Wnt/β-Catenin Signaling Pathways
por: Mandal, Animesh, et al.
Publicado: (2015)

Report on Second International Conference on Natural Products for Cancer Prevention and Therapy Held in Kayseri, Turkey, 8–11 November 2017
por: Yerer, Mükerrem Betül, et al.
Publicado: (2017)

Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways
por: Mandal, Animesh, et al.
Publicado: (2017)

On a Beam of Light: Photoprotective Activities of the Marine Carotenoids Astaxanthin and Fucoxanthin in Suppression of Inflammation and Cancer
por: Catanzaro, Elena, et al.
Publicado: (2020)

Black tea bioactive phytoconstituents realign NRF2 for anticancer activity in lung adenocarcinoma
por: Datta, Suchisnigdha, et al.
Publicado: (2023)

Analgesic and Anti-Inflammatory Activities of Quercetin-3-methoxy-4′-glucosyl-7-glucoside Isolated from Indian Medicinal Plant Melothria heterophylla
por: Mondal, Arijit, et al.
Publicado: (2019)

Sequential activation of Elk-1/Egr-1/GADD45α by arsenic
por: Shi, Qiwen, et al.
Publicado: (2014)

Targeting Histone Deacetylases with Natural and Synthetic Agents: An Emerging Anticancer Strategy
por: Singh, Amit Kumar, et al.
Publicado: (2018)

Emerging Concepts of Hybrid Epithelial-to-Mesenchymal Transition in Cancer Progression
por: Sinha, Dona, et al.
Publicado: (2020)

Antitumor Potential of Marine and Freshwater Lectins
por: Catanzaro, Elena, et al.
Publicado: (2019)

A Novel Tetraenoic Fatty Acid Isolated from Amaranthus spinosus Inhibits Proliferation and Induces Apoptosis of Human Liver Cancer Cells
por: Mondal, Arijit, et al.
Publicado: (2016)

Targeting Ubiquitin-Proteasome Pathway by Natural Products: Novel Therapeutic Strategy for Treatment of Neurodegenerative Diseases
por: Momtaz, Saeideh, et al.
Publicado: (2020)

Marine Sponge Natural Products with Anticancer Potential: An Updated Review
por: Calcabrini, Cinzia, et al.
Publicado: (2017)

Cirsiliol Suppressed Epithelial to Mesenchymal Transition in B16F10 Malignant Melanoma Cells through Alteration of the PI3K/Akt/NF-κB Signaling Pathway
por: Prasad, Priyanka, et al.
Publicado: (2019)

Autophagy: A Potential Therapeutic Target of Polyphenols in Hepatocellular Carcinoma
por: Kiruthiga, Chandramohan, et al.
Publicado: (2020)

A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies
por: Ghanbari-Movahed, Maryam, et al.
Publicado: (2021)

Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres
por: Sukocheva, Olga A., et al.
Publicado: (2021)

Trends in Research on Exosomes in Cancer Progression and Anticancer Therapy
por: Sinha, Dona, et al.
Publicado: (2021)

A Pleiotropic Role of Long Non-Coding RNAs in the Modulation of Wnt/β-Catenin and PI3K/Akt/mTOR Signaling Pathways in Esophageal Squamous Cell Carcinoma: Implication in Chemotherapeutic Drug Response
por: Sharma, Uttam, et al.
Publicado: (2022)

Lotus (Nelumbo nucifera Gaertn.) and Its Bioactive Phytocompounds: A Tribute to Cancer Prevention and Intervention
por: Bishayee, Anupam, et al.
Publicado: (2022)

Correction: Bishayee et al. Lotus (Nelumbo nucifera Gaertn.) and Its Bioactive Phytocompounds: A Tribute to Cancer Prevention and Intervention. Cancers 2022, 14, 529
por: Bishayee, Anupam, et al.
Publicado: (2022)

Gossypol and Its Natural Derivatives: Multitargeted Phytochemicals as Potential Drug Candidates for Oncologic Diseases
por: Pal, Dilipkumar, et al.
Publicado: (2022)

CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells
por: Shi, Qiwen, et al.
Publicado: (2015)

The Antioxidant and Antihyperglycemic Activities of Bottlebrush Plant (Callistemon lanceolatus) Stem Extracts
por: Kumar, Ramesh, et al.
Publicado: (2020)

Oncogenic and Tumor Suppressive Components of the Cell Cycle in Breast Cancer Progression and Prognosis
por: Kashyap, Dharambir, et al.
Publicado: (2021)

Recent Advances in Improved Anticancer Efficacies of Camptothecin Nano-Formulations: A Systematic Review
por: Ghanbari-Movahed, Maryam, et al.
Publicado: (2021)

Targeting Cell Signaling Pathways in Lung Cancer by Bioactive Phytocompounds
por: Choudhary, Neeraj, et al.
Publicado: (2023)

Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital.
por: Bishayee, A., et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_appbi6aur2naogu283dkl07eiv