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Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT(1A) and D(2) Receptors

The increasing number of patients reporting depressive symptoms requires the design of new antidepressants with higher efficacy and limited side effects. As our previous research showed, 2-methoxyphenylpiperazine derivatives are promising candidates to fulfill these criteria. In this study, we aimed...

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Detalles Bibliográficos
Autores principales: Sałaciak, Kinga, Malikowska-Racia, Natalia, Lustyk, Klaudia, Siwek, Agata, Głuch-Lutwin, Monika, Kazek, Grzegorz, Popiół, Justyna, Sapa, Jacek, Marona, Henryk, Żelaszczyk, Dorota, Pytka, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400343/
https://www.ncbi.nlm.nih.gov/pubmed/34451841
http://dx.doi.org/10.3390/ph14080744

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