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Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold
PURPOSE: This study assessed the clinical outcomes of periprosthetic joint infection patients who underwent two-stage revision total knee arthroplasty with antibiotic-loaded cement spacers fabricated using a handmade silicone mold. MATERIALS AND METHODS: This study included seven patients (average a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400397/ https://www.ncbi.nlm.nih.gov/pubmed/34454632 http://dx.doi.org/10.1186/s43019-021-00113-3 |
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author | Hoshino, Takashi Watanabe, Toshifumi Nakagawa, Yusuke Katagiri, Hiroki Ozeki, Nobutake Ohara, Toshiyuki Shioda, Mikio Kono, Yuji Sekiya, Ichiro Koga, Hideyuki |
author_facet | Hoshino, Takashi Watanabe, Toshifumi Nakagawa, Yusuke Katagiri, Hiroki Ozeki, Nobutake Ohara, Toshiyuki Shioda, Mikio Kono, Yuji Sekiya, Ichiro Koga, Hideyuki |
author_sort | Hoshino, Takashi |
collection | PubMed |
description | PURPOSE: This study assessed the clinical outcomes of periprosthetic joint infection patients who underwent two-stage revision total knee arthroplasty with antibiotic-loaded cement spacers fabricated using a handmade silicone mold. MATERIALS AND METHODS: This study included seven patients (average age 77 years, average follow-up time 54 months) who underwent surgery at our hospital between 2009 and 2013. Clinical outcomes including knee scores, function scores, knee range of motion, and walking ability at the final observation, period from the primary total knee arthroplasty to implant removal, period from implant removal to revision total knee arthroplasty, and follow-up period after revision total knee arthroplasty were investigated. RESULTS: At the final follow-up, the average knee range of motion was 99°, with no significant differences at each stage; average knee and function scores were 84 and 77, respectively. With cement spacers, five patients were able to walk with a t-cane. No recurrence of infection was observed. CONCLUSIONS: The clinical outcomes of the current case series demonstrated good knee function with preserved walking ability, without any recurrence of periprosthetic joint infection. This study suggests that using a handmade silicone mold could be an effective option for periprosthetic joint infection after a total knee arthroplasty. |
format | Online Article Text |
id | pubmed-8400397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-84003972021-09-09 Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold Hoshino, Takashi Watanabe, Toshifumi Nakagawa, Yusuke Katagiri, Hiroki Ozeki, Nobutake Ohara, Toshiyuki Shioda, Mikio Kono, Yuji Sekiya, Ichiro Koga, Hideyuki Knee Surg Relat Res Research Article PURPOSE: This study assessed the clinical outcomes of periprosthetic joint infection patients who underwent two-stage revision total knee arthroplasty with antibiotic-loaded cement spacers fabricated using a handmade silicone mold. MATERIALS AND METHODS: This study included seven patients (average age 77 years, average follow-up time 54 months) who underwent surgery at our hospital between 2009 and 2013. Clinical outcomes including knee scores, function scores, knee range of motion, and walking ability at the final observation, period from the primary total knee arthroplasty to implant removal, period from implant removal to revision total knee arthroplasty, and follow-up period after revision total knee arthroplasty were investigated. RESULTS: At the final follow-up, the average knee range of motion was 99°, with no significant differences at each stage; average knee and function scores were 84 and 77, respectively. With cement spacers, five patients were able to walk with a t-cane. No recurrence of infection was observed. CONCLUSIONS: The clinical outcomes of the current case series demonstrated good knee function with preserved walking ability, without any recurrence of periprosthetic joint infection. This study suggests that using a handmade silicone mold could be an effective option for periprosthetic joint infection after a total knee arthroplasty. BioMed Central 2021-08-28 /pmc/articles/PMC8400397/ /pubmed/34454632 http://dx.doi.org/10.1186/s43019-021-00113-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Hoshino, Takashi Watanabe, Toshifumi Nakagawa, Yusuke Katagiri, Hiroki Ozeki, Nobutake Ohara, Toshiyuki Shioda, Mikio Kono, Yuji Sekiya, Ichiro Koga, Hideyuki Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title | Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title_full | Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title_fullStr | Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title_full_unstemmed | Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title_short | Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
title_sort | clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400397/ https://www.ncbi.nlm.nih.gov/pubmed/34454632 http://dx.doi.org/10.1186/s43019-021-00113-3 |
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