Cargando…

Functional Duality of Chondrocyte Hypertrophy and Biomedical Application Trends in Osteoarthritis

Chondrocyte hypertrophy is one of the key indicators in the progression of osteoarthritis (OA). However, compared with other OA indications, such as cartilage collapse, sclerosis, inflammation, and protease activation, the mechanisms by which chondrocyte hypertrophy contributes to OA remain elusive....

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Sunghyun, Bello, Alvin, Arai, Yoshie, Ahn, Jinsung, Kim, Dohyun, Cha, Kyung-Yup, Baek, Inho, Park, Hansoo, Lee, Soo-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400409/ https://www.ncbi.nlm.nih.gov/pubmed/34452101 http://dx.doi.org/10.3390/pharmaceutics13081139

Ejemplares similares

SPRY4 acts as an indicator of osteoarthritis severity and regulates chondrocyte hypertrophy and ECM protease expression
por: Park, Sunghyun, et al.
Publicado: (2021)

Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration
por: Bello, Alvin Bacero, et al.
Publicado: (2021)

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
por: Rim, Yeri Alice, et al.
Publicado: (2020)

Therapeutic potential of epiphyseal growth plate cells for bone regeneration in an osteoporosis model
por: Baek, Inho, et al.
Publicado: (2022)

Matrilin-3-Primed Adipose-Derived Mesenchymal Stromal Cell Spheroids Prevent Mesenchymal Stromal-Cell-Derived Chondrocyte Hypertrophy
por: Muttigi, Manjunatha S., et al.
Publicado: (2020)

Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)
por: Prakash, Nityanand, et al.
Publicado: (2023)

Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3
por: Yahara, Yasuhito, et al.
Publicado: (2016)

Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies
por: Chawla, Shikha, et al.
Publicado: (2022)

Corrigendum: Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3
por: Yahara, Yasuhito, et al.
Publicado: (2016)

Neural cell adhesion molecule regulates chondrocyte hypertrophy in chondrogenic differentiation and experimental osteoarthritis
por: Cheng, Bin‐Feng, et al.
Publicado: (2019)

Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
por: Ebata, Taku, et al.
Publicado: (2021)

Anti-Dlx5 Retards the Progression of Osteoarthritis through Inhibiting Chondrocyte Hypertrophy and Apoptosis
por: Lu, Ye, et al.
Publicado: (2022)

Efficient Isolation and Enrichment of Mesenchymal Stem Cells from Human Embryonic Stem Cells by Utilizing the Interaction between Integrin α5β1 and Fibronectin
por: Cha, Byung‐Hyun, et al.
Publicado: (2020)

Down-Regulation of Transglutaminase 2 Stimulates Redifferentiation of Dedifferentiated Chondrocytes through Enhancing Glucose Metabolism
por: Ko, Kyoung-Won, et al.
Publicado: (2017)

Influence of cationic lipid concentration on properties of lipid–polymer hybrid nanospheres for gene delivery
por: Bose, Rajendran JC, et al.
Publicado: (2015)

Induction and prevention of chondrocyte hypertrophy in culture
Publicado: (1989)

The synovial microenvironment suppresses chondrocyte hypertrophy and promotes articular chondrocyte differentiation
por: Chau, Michael, et al.
Publicado: (2022)

Wogonoside inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis
por: Tang, Qian, et al.
Publicado: (2017)

HDAC4 mutant represses chondrocyte hypertrophy by locating in the nucleus and attenuates disease progression of posttraumatic osteoarthritis
por: Gu, Xiaodong, et al.
Publicado: (2022)

DLX5 promotes Col10a1 expression and chondrocyte hypertrophy and is involved in osteoarthritis progression
por: Chen, Jinnan, et al.
Publicado: (2023)

Crosslinking method of hyaluronic-based hydrogel for biomedical applications
por: Khunmanee, Sureerat, et al.
Publicado: (2017)

A co-adaptive duality-aware framework for biomedical relation extraction
por: Zhang, Weiyan, et al.
Publicado: (2023)

Suppressing Chondrocyte Hypertrophy to Build Better Cartilage
por: Shigley, Christian, et al.
Publicado: (2023)

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis
por: Garcia de Vinuesa, Amaya, et al.
Publicado: (2021)

AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal
por: Ahn, J, et al.
Publicado: (2016)

Stromal Cell-Derived Factor 1 Regulates the Actin Organization of Chondrocytes and Chondrocyte Hypertrophy
por: Murata, Koichi, et al.
Publicado: (2012)

Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features
por: Geurts, Jeroen, et al.
Publicado: (2020)

Natural bio-based monomers for biomedical applications: a review
por: Birajdar, Mallinath S., et al.
Publicado: (2021)

Osteoblast-Chondrocyte Interactions in Osteoarthritis
por: Findlay, David M., et al.
Publicado: (2014)

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Chondrocyte death involvement in osteoarthritis
por: Salucci, S., et al.
Publicado: (2022)

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner
por: Zheng, Lihua, et al.
Publicado: (2007)

A Qualitative Model of the Differentiation Network in Chondrocyte Maturation: A Holistic View of Chondrocyte Hypertrophy
por: Kerkhofs, Johan, et al.
Publicado: (2016)

Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1−SMAD1 interaction
por: Lian, Chengjie, et al.
Publicado: (2019)

Matrilin-3 Role in Cartilage Development and Osteoarthritis
por: Muttigi, Manjunatha S., et al.
Publicado: (2016)

Toric Duality as Seiberg Duality and Brane Diamonds
por: Feng, Bo, et al.
Publicado: (2001)

Lithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte Phenotype of Obese Osteoarthritis Patients
por: Guidotti, Serena, et al.
Publicado: (2015)

Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification
por: Morita, Kozo, et al.
Publicado: (2007)

Oxidative stress induces chondrocyte telomere instability and chondrocyte dysfunctions in osteoarthritis
por: Yudoh, K, et al.
Publicado: (2003)

A-twisted correlators and Hori dualities
por: Closset, Cyril, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s503g7bh5vhvarlij4eifkpusc