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Limited HIV-1 Subtype C nef 3′PPT Variation in Combination Antiretroviral Therapy Naïve and Experienced People Living with HIV in Botswana

Dolutegravir (DTG) is a potent anti-HIV drug that is used to treat HIV globally. There have been reports of mutations in the HIV-1 3′-polypurine tract (3′PPT) of the nef gene, contributing to DTG failure; however, there are limited ‘real-world’ data on this. In addition, there is a knowledge gap on...

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Detalles Bibliográficos
Autores principales:	Seatla, Kaelo K., Maruapula, Dorcas, Choga, Wonderful T., Morerinyane, Olorato, Lockman, Shahin, Novitsky, Vladimir, Kasvosve, Ishmael, Moyo, Sikhulile, Gaseitsiwe, Simani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400509/ https://www.ncbi.nlm.nih.gov/pubmed/34451492 http://dx.doi.org/10.3390/pathogens10081027

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