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Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold

A quinoxaline scaffold exhibits various bioactivities in pharmacotherapeutic interests. In this research, twelve quinoxaline derivatives were synthesized and evaluated as new acetylcholinesterase inhibitors. We found all compounds showed potent inhibitory activity against acetylcholinesterase (AChE)...

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Detalles Bibliográficos
Autores principales:	Suwanhom, Paptawan, Saetang, Jirakrit, Khongkow, Pasarat, Nualnoi, Teerapat, Tipmanee, Varomyalin, Lomlim, Luelak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400540/ https://www.ncbi.nlm.nih.gov/pubmed/34443482 http://dx.doi.org/10.3390/molecules26164895

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