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The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importance of this oncogenic protein in disease pathogenesis....

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Detalles Bibliográficos
Autores principales: Davis, Alexandra M, Rapley, Abigail, Dawson, Christopher W, Young, Lawrence S, Morris, Mhairi A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400670/
https://www.ncbi.nlm.nih.gov/pubmed/34451446
http://dx.doi.org/10.3390/pathogens10080982

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