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Cyclin G2 reverses immunosuppressive tumor microenvironment and potentiates PD-1 blockade in glioma

BACKGROUND: Expression of aberrant cyclin G2 is a key factor contributing to cancer biological processes, including glioma. However, the potential underlying mechanisms of cyclin G2 in the glioma tumor immune microenvironment remain unclear. METHODS: Co-immunoprecipitation (co-IP), in situ proximity...

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Detalles Bibliográficos
Autores principales: Li, Sen, Zhao, Chenyang, Gao, Jinlan, Zhuang, Xinbin, Liu, Shuang, Xing, Xuesha, Liu, Qi, Chen, Chen, Wang, Shusen, Luo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400712/
https://www.ncbi.nlm.nih.gov/pubmed/34452627
http://dx.doi.org/10.1186/s13046-021-02078-3