A Fully Human Monoclonal Antibody Targeting cKIT Is a Potent Inhibitor of Pathological Choroidal Neovascularization in Mice

Stem cell factor (SCF) and its receptor, cKIT, are novel regulators of pathological neovascularization in the eye, which suggests that inhibition of SCF/cKIT signaling may be a novel pharmacological strategy for treating neovascular age-related macular degeneration (AMD). This study evaluated the th...

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Detalles Bibliográficos
Autores principales: Seo, Songyi, Kim, Koung Li, Yeo, Yeongju, Kim, Ryul-I, Jeong, Hayoung, Kim, Jin-Ock, Song, Sun-Hwa, An, Mi-Jin, Kim, Jung-Woong, Hong, Hye Kyoung, Ham, Min Hee, Woo, Se Joon, Sung, Jong-Hyuk, Park, Sang Gyu, Suh, Wonhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400730/
https://www.ncbi.nlm.nih.gov/pubmed/34452268
http://dx.doi.org/10.3390/pharmaceutics13081308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400730/
https://www.ncbi.nlm.nih.gov/pubmed/34452268
http://dx.doi.org/10.3390/pharmaceutics13081308

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