Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors

Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the f...

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Autores principales: Šponer, Judit E., Šponer, Jiří, Kovařík, Aleš, Šedo, Ondrej, Zdráhal, Zbyněk, Costanzo, Giovanna, Di Mauro, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400769/
https://www.ncbi.nlm.nih.gov/pubmed/34440544
http://dx.doi.org/10.3390/life11080800
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author Šponer, Judit E.
Šponer, Jiří
Kovařík, Aleš
Šedo, Ondrej
Zdráhal, Zbyněk
Costanzo, Giovanna
Di Mauro, Ernesto
author_facet Šponer, Judit E.
Šponer, Jiří
Kovařík, Aleš
Šedo, Ondrej
Zdráhal, Zbyněk
Costanzo, Giovanna
Di Mauro, Ernesto
author_sort Šponer, Judit E.
collection PubMed
description Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the field of prebiotic chemistry. The aim of the current review is to answer the most frequently raised questions related to the detection and characterization of oligomeric products as well as to the geological context of this chemistry.
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spelling pubmed-84007692021-08-29 Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors Šponer, Judit E. Šponer, Jiří Kovařík, Aleš Šedo, Ondrej Zdráhal, Zbyněk Costanzo, Giovanna Di Mauro, Ernesto Life (Basel) Review Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process. These works evoked a vivid discussion among scientists working in the field of prebiotic chemistry. The aim of the current review is to answer the most frequently raised questions related to the detection and characterization of oligomeric products as well as to the geological context of this chemistry. MDPI 2021-08-08 /pmc/articles/PMC8400769/ /pubmed/34440544 http://dx.doi.org/10.3390/life11080800 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Šponer, Judit E.
Šponer, Jiří
Kovařík, Aleš
Šedo, Ondrej
Zdráhal, Zbyněk
Costanzo, Giovanna
Di Mauro, Ernesto
Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title_full Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title_fullStr Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title_full_unstemmed Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title_short Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
title_sort questions and answers related to the prebiotic production of oligonucleotide sequences from 3′,5′ cyclic nucleotide precursors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400769/
https://www.ncbi.nlm.nih.gov/pubmed/34440544
http://dx.doi.org/10.3390/life11080800
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