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Discovery of Amide-Functionalized Benzimidazolium Salts as Potent α-Glucosidase Inhibitors
α-Glucosidase inhibitors (AGIs) are used as medicines for the treatment of diabetes mellitus. The α-Glucosidase enzyme is present in the small intestine and is responsible for the breakdown of carbohydrates into sugars. The process results in an increase in blood sugar levels. AGIs slow down the dig...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400806/ https://www.ncbi.nlm.nih.gov/pubmed/34443347 http://dx.doi.org/10.3390/molecules26164760 |