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Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake

The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI)...

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Autores principales: Dobrzyńska, Małgorzata, Drzymała-Czyż, Sławomira, Jakubowski, Karol, Kurek, Szymon, Walkowiak, Jarosław, Przysławski, Juliusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400833/
https://www.ncbi.nlm.nih.gov/pubmed/34444702
http://dx.doi.org/10.3390/nu13082542
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author Dobrzyńska, Małgorzata
Drzymała-Czyż, Sławomira
Jakubowski, Karol
Kurek, Szymon
Walkowiak, Jarosław
Przysławski, Juliusz
author_facet Dobrzyńska, Małgorzata
Drzymała-Czyż, Sławomira
Jakubowski, Karol
Kurek, Szymon
Walkowiak, Jarosław
Przysławski, Juliusz
author_sort Dobrzyńska, Małgorzata
collection PubMed
description The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI) of both micronutrients was estimated. Cu and Zn concentration in 103 formulae for infants, available in the Polish market, were assessed using atomic absorption spectrometry. The estimated DI was calculated from the average energy requirements for the 0–6 months aged infants. The microelement content of formulae was mostly in good agreement with that declared by the manufacturer (5–10% variations compared to the labeled values). The Cu/Zn ratio ranged from 1:8 to 1:25. The estimated DI of Cu was in the range of 0.14–1.11 mg/day. Six (6.7%) of the formulae did not meet the recommended range of Cu intake, especially during the first month of life and in the case of formulae for special medical purposes. The estimated DI of Zn varied from 2.27–11.25 mg/day. In most cases, the concentration of Cu and Zn in infant formulae was within the recommended range. It would be advisable to consider monitoring the DI of Cu and reconsider the Cu content in formulae for infants in proportion to its expected consumption.
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spelling pubmed-84008332021-08-29 Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake Dobrzyńska, Małgorzata Drzymała-Czyż, Sławomira Jakubowski, Karol Kurek, Szymon Walkowiak, Jarosław Przysławski, Juliusz Nutrients Article The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI) of both micronutrients was estimated. Cu and Zn concentration in 103 formulae for infants, available in the Polish market, were assessed using atomic absorption spectrometry. The estimated DI was calculated from the average energy requirements for the 0–6 months aged infants. The microelement content of formulae was mostly in good agreement with that declared by the manufacturer (5–10% variations compared to the labeled values). The Cu/Zn ratio ranged from 1:8 to 1:25. The estimated DI of Cu was in the range of 0.14–1.11 mg/day. Six (6.7%) of the formulae did not meet the recommended range of Cu intake, especially during the first month of life and in the case of formulae for special medical purposes. The estimated DI of Zn varied from 2.27–11.25 mg/day. In most cases, the concentration of Cu and Zn in infant formulae was within the recommended range. It would be advisable to consider monitoring the DI of Cu and reconsider the Cu content in formulae for infants in proportion to its expected consumption. MDPI 2021-07-25 /pmc/articles/PMC8400833/ /pubmed/34444702 http://dx.doi.org/10.3390/nu13082542 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dobrzyńska, Małgorzata
Drzymała-Czyż, Sławomira
Jakubowski, Karol
Kurek, Szymon
Walkowiak, Jarosław
Przysławski, Juliusz
Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_full Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_fullStr Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_full_unstemmed Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_short Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_sort copper and zinc content in infant milk formulae available on the polish market and contribution to dietary intake
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400833/
https://www.ncbi.nlm.nih.gov/pubmed/34444702
http://dx.doi.org/10.3390/nu13082542
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