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Ion-Triggered In Situ Gelling Nanoemulgel as a Platform for Nose-to-Brain Delivery of Small Lipophilic Molecules
Background: Intranasal route offers a direct nose-to-brain delivery via olfactory and trigeminal nerves and minimizes the systemic exposure of the drug. Although reliable and non-invasive, intranasal administration of lipophilic neuroprotective agents for brain targeting is still challenging. Litera...
Autores principales: | Nagaraja, Sreeharsha, Basavarajappa, Girish Meravanige, Karnati, Ranjith Kumar, Bakir, Esam Mohamed, Pund, Swati |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400950/ https://www.ncbi.nlm.nih.gov/pubmed/34452177 http://dx.doi.org/10.3390/pharmaceutics13081216 |
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