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Exploring the Early Stages of the Amyloid Aβ(1–42) Peptide Aggregation Process: An NMR Study

Alzheimer’s disease (AD) is a neurodegenerative pathology characterized by the presence of neurofibrillary tangles and amyloid plaques, the latter mainly composed of Aβ(1–40) and Aβ(1–42) peptides. The control of the Aβ aggregation process as a therapeutic strategy for AD has prompted the interest t...

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Detalles Bibliográficos
Autores principales: Santoro, Angelo, Grimaldi, Manuela, Buonocore, Michela, Stillitano, Ilaria, D’Ursi, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400958/
https://www.ncbi.nlm.nih.gov/pubmed/34451828
http://dx.doi.org/10.3390/ph14080732